Author(s):
Silva, Tiago H. 
; Alves, A. ; Ferreira, B. M. ; Oliveira, Joaquim M. ; Reys, L. L. ; Ferreira, R. J. F. ; Sousa, R. A. ; Silva, S. S. ; Mano, J. F. ; Reis, R. L.
Date: 2012
Persistent ID: http://hdl.handle.net/1822/21720
Origin: RepositóriUM - Universidade do Minho
Subject(s): Marine origin materials; Marine biomaterials; Biopolymers; Chitosan; Alginate; Carrageenans; Calcium phosphates; Biosilica; Biomedical applications; Tissue engineering; Review
Description
Marine organisms are constituted by materials with a vast range of properties and characteristics that may justify their potential application within the biomedical field. Moreover, assuring the sustainable exploitation of natural marine resources, the valorisation of residues from marine origin, like those obtained from food processing, constitutes a highly interesting platform for
development of novel biomaterials, with both economic and environmental benefits. In this perspective, an increasing number of different types of compounds are being isolated from aquatic organisms and transformed into profitable products for health applications, including controlled drug delivery and tissue engineering devices. This report reviews the work that is being developed on the isolation and characterisation of some polysaccharides, proteins, glycosaminoglycans and ceramics from marine raw materials. Emphasis is given to agar, alginates, carrageenans, chitin and chitosan, among other polysaccharides, collagen, glycosaminoglycans such as chondroitin sulphate, heparin and hyaluronic acid, calcium phosphorous compounds and biosilica. Finally, this report ends by reviewing the application of the previously mentioned materials on specific biomedical applications, in particular their participation on the development of controlled drug delivery systems and tissue engineering scaffolds.
