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Revealing the potential of squid chitosan-based structures for biomedical appli...

In recent years, much attention has been given to different marine organisms, namely as potential sources of valuable materials with a vast range of properties and characteristics. In this work, β-chitin was isolated from the endoskeleton of the giant squid Dosidicus gigas and further deacetylated to produce chitosan. Then, the squid chitosan was processed into membranes and scaffolds using solvent casting and ...

Biomedical exploitation of squid chitosan using particle aggregation derived co...

Publicado em "Journal of Tissue Engineering and Regenerative Medicine", vol. 7, supp. 1 (2013) ; In the last decades, marine organisms have been the focus of considerable attention as potential source of valuable materials. Some important examples are β-chitin isolated from the endoskeleton of squids and hydroxyapatite (HA) produced from fish-bones. β-chitin is a structural polysaccharide more reactive than th...

Cartilage regeneration approach based on squid chitosan scaffolds : in-vitro as...

During the past decades, marine organisms have been the focus of considerable attention as potential source of valuable materials. For instance, chitosan is a biopolymer with high potential in the biomedical field and can be produced from crustacean shells and squid pens [1]. In this sense, we propose the use of chitosan to produce scaffolds for regenerative medicine purposes. An alkaline solution was used to d...

Development of marine-based nanocomposite scaffolds for biomedical applications

Despite the increasing attention that marine organisms are receiving, many of those are not efficiently exploited and subproducts with valuable compounds are being discarded. Two examples of those subproducts are the endoskeleton of squid, from which β-­‐chitin and consecutively chitosan can be obtained; and fish-­‐bones, as a source for the production of nano-­‐ hydroxyapatite. In this work, inspired in the na...

The use of ionic liquids in the processing of chitosan/silk hydrogels for biome...

Natural polymers are adequate renewable resources for the processability of well-defined architectures for several applications. Combinations of polysaccharides and proteins may mimic the naturally occurring environment of certain tissues. The main goal of this work renders the application of green chemistry principles, namely the use of ionic liquids (ILs) and biorenewable sources, such as chitosan (CHT) and s...

Materials of marine origin : a review on polymers and ceramics of biomedical in...

Marine organisms are constituted by materials with a vast range of properties and characteristics that may justify their potential application within the biomedical field. Moreover, assuring the sustainable exploitation of natural marine resources, the valorisation of residues from marine origin, like those obtained from food processing, constitutes a highly interesting platform for development of novel biomate...

Marine algae sulfated polysaccharides for tissue engineering and drug delivery ...

Biomedical field is constantly requesting for new biomaterials, with innovative properties. Natural polymers appear as materials of election for this goal due to their biocompatibility and biodegradability. In particular, materials found in marine environment are of great interest since the chemical and biological diversity found in this environment is almost uncountable and continuously growing with the resear...

Valorization of chitosan from squid pens and further use on the development of ...

Objectives: The aim of the present work is the valorization of squid pens through the production of chitosan that can be used for the development of biomedical applications. The present work is focused on !-chitin extraction from squid pens of the species Dosidicus gigas and its further conversion into chitosan. The biomedical potential of the isolated squid chitosan was assessed by processing this polymer as s...

Clinical research in critically ill patients.

Some of the ethical and legal problems raised by medical research involving critical care patients are analysed and discussed. Particular attention is given to the difficulties of obtaining informed consent from patients that most of the times are not considered competent from the legal point of view to give it. Careful thought must also be given to the weighting of risks of the procedures against the expected ...

Legal medicine in the hospital.