Macro/micro porous silk fibroin scaffolds obtained via combined methodologies f...

• Author(s): Yan, Leping ; Oliveira, Joaquim M. ; Oliveira, Ana Leite ; Caridade, S. G. ; Mano, J. F. ; Reis, R. L.
• Date: 2011
• Persistent ID: http://hdl.handle.net/1822/12833
• Origin: RepositóriUM - Universidade do Minho
• Subject(s): Silk fibroin; Salt leaching; Porous scaffold; Articular cartilage; Meniscus; Tissue engineering
• Document Type: Conference Object
• Language: English

Description

This study proved that the salt leached silk fibroin scaffolds can be developed by using more than 10 wt% aqueous silk fibroin solutions. There were some previous studies shown that this was impossible. This work has shown that the developed silk fibroin scaffolds can combine adequate mechanical properties with a unique morphology which make them suitable to be used in tissue engineering applications, particularly for cartilage and meniscus regeneration.