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Macro/microporous silk fibroin scaffolds with potential for articular cartilage...
Yan, Leping; Oliveira, Joaquim M.; Oliveira, Ana Leite; Caridade, S. G.; Mano, J. F.; Reis, R. L.This study describes the developmental physicochemical properties of silk fibroin scaffolds derived from high concentration aqueous silk fibroin solutions. The silk fibroin scaffolds were prepared with different initial concentrations (8%, 10%, 12% and 16% (wt%)) and obtained by combining the salt-leaching and freeze-drying methodologies. The results indicated that the antiparallel β-pleated sheet (silk-II) con...
Macro/micro porous silk fibroin scaffolds obtained via combined methodologies f...
Yan, Leping; Oliveira, Joaquim M.; Oliveira, Ana Leite; Caridade, S. G.; Mano, J. F.; Reis, R. L.This study proved that the salt leached silk fibroin scaffolds can be developed by using more than 10 wt% aqueous silk fibroin solutions. There were some previous studies shown that this was impossible. ; This work has shown that the developed silk fibroin scaffolds can combine adequate mechanical properties with a unique morphology which make them suitable to be used in tissue engineering applications, partic...
New biomimetic approaches for producing bone-like calcium-phosphate coatings on...
Oliveira, Ana LeiteTese de Doutoramento em Ciência e Engenharia de Polímeros - Área de Conhecimento em Ciência de Materiais Poliméricos ; Bone is one of the most wonderful examples of nature’s ability to engineer living materials. The processes by which the mineralized tissues are formed can be a source of information for the development of new materials for biomedical applications, capable of better mimicking living tissues, i....
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