Pharmacological properties of Tilia europeæ aqueous: screening anxiolytic/sedat...

• Author(s): Cotrim, M. D. ; Figueiredo, I. V. ; Cavadas, C. ; Cunha, A. Proença da ; Caramona, M. M. ; Macedo, T. R. A.
• Date: 2005
• Persistent ID: http://hdl.handle.net/10316/14662
• Origin: Estudo Geral - Universidade de Coimbra
• Subject(s): Tilia europeae; Anxiolytic effect; Sedation; Locomotion; Exploration
• Document Type: Article
• Language: English

Description

The extracts or infusions obtained from inflorescences of Tilia europeae have been used in popular medicine as a sedative/anxiolytic drug. The purpose of the present work was to evaluate these possible properties of this extract, by using different behavioural models. The extract, orally administered to mice, prolonged sleeping time, changed the level of anxiety, affected curiosity and locomotor activity and showed miorrelaxant properties. JNICT PBIC/C/SAU/1607/92