Matrix Gla protein expression: a complex process involving the use of alternati...

• Autor(es): Cancela, Leonor ; Laizé, Vincent ; Conceição, N. ; Tiago, Daniel M. ; Maia, A. T. ; Bensimon-Brito, A. ; Gavaia, Paulo J.
• Data: 2012
• Identificador Persistente: http://hdl.handle.net/10400.1/4469
• Origem: Sapientia - Universidade do Algarve
• Tipo de Documento: Documento de conferência
• Idioma: Inglês

Descrição

Matrix Gla protein (MGP) is a secreted vitamin K-dependent protein (VKD) located in the extracellular matrix and capable of binding calcium through its -carboxyglutamate residues. Although identified in 1983, transcriptional and post-transcriptional mechanisms regulating its expression remain unclear.