Encontrados 26 documentos, a visualizar página 1 de 3
Temporal and spatial expression patterns of pregnane X receptor and vitamin K e...
Fernández, Ignacio; Cancela, Leonor; Gavaia, Paulo J.Vitamin K (VK) is a liposoluble vitamin known to be essential for bone metabolism by two different pathways: (i) by its role as a coenzyme in the gamma-carboxylation of some skeletal proteins (e.g. osteocalcin (OC) and matrix Gla protein (MGP); Price et al., 1998); and (ii) through its role in skeletal gene transcription via binding to the pregnane X receptor (PXR; Azuma et al., 2010).
Matrix Gla protein expression: a complex process involving the use of alternati...
Cancela, Leonor; Laizé, Vincent; Conceição, N.; Tiago, Daniel M.; Maia, A. T.; Bensimon-Brito, A.; Gavaia, Paulo J.Matrix Gla protein (MGP) is a secreted vitamin K-dependent protein (VKD) located in the extracellular matrix and capable of binding calcium through its -carboxyglutamate residues. Although identified in 1983, transcriptional and post-transcriptional mechanisms regulating its expression remain unclear.
Skeletal quality in Senegalese sole: characterization of fish resulting from en...
Gavaia, Paulo J.; Dionísio, G.; Cardeira, J.; Cunha, M. E.; Pousão-Ferreira, P.; Conceição, L. E. C.; Cancela, LeonorThe Senegalese sole (Solea senegalensis) is characteristic from southern Europe and Mediterranean. It has recently been adapted for aquaculture production since it is well accepted by consumers and reaches high commercial values. After the initial description of the ontogenic events of skeletogenesis, systematic evaluation of the incidence of skeletal malformations by several groups revealed high levels of skel...
Two isoforms of vasa maternal factor in Senegalese sole: Biotechnological appli...
Pacchiarini, T.; Cabrita, E.; Cross, I.; Ortiz-Delgado, J. B.; Leite, Ricardo B.; Gavaia, Paulo J.; Herráez, M. P.; Rebordinos, L.; Sarasquete, C.Primordial Germ Cells (PGCs) identification and manipulation present considerable potential for hatchery practice and surrogate broodstocks. To carry out the PGCs characterization a specific molecular marker is required. The vasa gene is a good candidate to identify PGCs and others germinal cells (Nagasawa et al., 2009). The aim of this study was the cloning of the Solea senegalensis vasa cDNA and its expressio...
Fish larvae quality descriptors: an appraisal of methods for red porgy Pagrus p...
Andrade, Carlos A. P.; Nogueira, N.; Silva, Paula; Cordeiro, Nereida; Cunha, M. E.; Pousão-Ferreira, P.; Ribeira, Laura; Bandarra, N.; Gavaia, Paulo J.Quality control in fish hatcheries is of paramount importance to achieve the desired characteristics of larvae and fry, either for the market or release to the wild. Quality programmes are applied in a day to day basis having direct implications for production management and final costs of product. Most common criteria used for larval quality assessment are morphometrics, condition factor, histometrical indices...
Nutrition, quality and performance in marine fish larvae
Conceição, L. E. C.; Alves-Martins, D.; Engrola, S.; Gavaia, Paulo J.; Richard, N.; Aragão, C.O cultivo de larvas de peixes marinhos é caracterizado por altas mortalidades e por problemas de qualidade, nomeadamente malformações esqueléticas. A solução de parte destes problemas passa por uma melhor compreensão dos requisitos nutricionais. Este trabalho pretende fazer uma revisão de trabalhos recentes que demonstram como os aminoácidos, os ácidos gordos e a vitamina K, mas também o regime alimentar, podem...
Determinism and causative factors for morphological anomalies in reared Europea...
Boglione, C.; Fontagné, Stéphanie; Gavaia, Paulo J.; Gisbert, Enric; Kjorsvik, E.; Koumoundouros, Giorgos; Moren, M.; Moutou, K. A.; Witten, PaulThe presence of sublethal morphological deformities represents one of the main bottleneck of the industrial finfish hatchery production, resulting in major economic loss due to reduced growth and marketing ability of the final product, that has to be transformed (filets) or sold for fish flour. Furthermore, the elimination of deformed fishes from the productive cycle needs for periodic selections at present car...
Inclusion of protein hydrolysates in the diet of white seabream (Diplodus sargu...
Richard, N.; de Vareilles, M.; Gavaia, Paulo J.; Silva, Tomé S.; Cordeiro, O.; Yúfera, M.; Rodrigues, Pedro; Conceição, L. E. C.In order to investigate the effects of dietary protein hydrolysate on larval skeleton quality and larvae proteome expression, triplicate groups of white seabream (Diplodus sargus) larvae were co-fed from first-feeding onwards with live feed and three microencapsulated diets ir differing only on the molecular weight of their protein hydrolysate fraction.
Recent advances in nutrition of fish larval
Conceição, L. E. C.; Aragão, C.; Richard, N.; Engrola, S.; Gavaia, Paulo J.; Mira, S.; Dias, J.Os requisitos nutricionais de larvas de peixes são ainda mal compreendidos, o que leva a altas mortalidades e problemas de qualidade no seu cultivo. Este trabalho pretende fazer uma revisão de novas metodologias de investigação, tais como estudos com marcadores, genómica populacional, programação nutricional, génomica e proteómica funcionais, e fornecer ainda alguns exemplos das utilizações presentes e perspect...
Skeletal evaluation and technical improvements to decrease the incidence of ske...
Gavaia, Paulo J.; Richard, N.; Dâmaso, L.; Dinis, Maria Teresa; Pousão-Ferreira, P.; Engrola, S.; Conceição, L. E. C.; Cancela, LeonorThe appearance of skeletal deformities is a major problem associated to intensive, large-scale culture of fish species, affecting growth, development and ultimately, survival of produced fish. Although the mechanisms working behind it are still unclear, it is known that environmental, genetic and nutritional factors play fundamental roles. Given its importance as a vertebrate model to study skeleton-related dis...
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