Síndrome de Budd-Chiari e Trombocitopenia grave em doente com Lúpus Eritematoso...

• Author(s): Duarte, C ; Couto, M ; Inês, L ; Malcata, AB
• Date: 2007
• Persistent ID: http://hdl.handle.net/10400.4/327
• Origin: Repositório do Centro Hospitalar e Universitário de Coimbra
• Subject(s): Lúpus Eritematoso Sistémico; Síndrome Antifosfolipídico; Síndrome de Budd-Chiari; Trombocitopenia
• Document Type: Article
• Language: Portuguese

Description

Systemic Lupus Erythematosus (SLE) is a rheumatic autoimmune disease characterized by multisystemic involvement with a variable prognosis. The association with Antiphospholipid Syndrome (APS) occurs in about 36% of the patients, raising additional problems with treatment and monitoring of these patients. The authors report a clinical case of a girl with SLE and APS who represented Budd-Chiari Syndrome and severe thrombocytopenia. The patient had severe thrombotic event and simultaneously a high hemorrhagic risk due to thrombocytopenia. Long-term resolution of the thrombocytopenia was achieved with mycophenolate mofetil. Long-term anticoagulation for thrombosis prophylaxis is required