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Vasculite livedóide em doente com síndrome antifosfolípido

Serra, S; Saavedra, MJ; Salvador, MJ; Reis, JP; Malcata, AB

The authors present a clinical case of a 30 year old male patient admitted to the hospital for recurrent cyanosis and feet pain lasting for one year. In addition he presented bilateral purpuric lesions in the lateral maleolar region, one of which with ulceration. The finding of anticardiolipin antibodies associated with intraluminal thrombosis in the dermal vessels, allowed to conclude for Antiphospholipid synd...


A propósito de um caso de espessamento cutâneo

Serra, S; Ambrósio, C; Salvador, MJ; Silva, J; Serra, D; Reis, JP; Malcata, AB

The authors present a clinical case of a 79 years old female patient, with a progressive cutaneous thickening of the face, trunk and limbs, lasting for 6 years. She also presented exertional dyspnea and intermittent solid dysphagia. The laboratory study identified IgG KAPA monoclonal protein and antinuclear antibodies with a speckled pattern. The nailfold capillaroscopy was normal. A detailed physical examinati...



Qualidade de vida e vivência da dor crónica nas doenças reumáticas

Oliveira, P; Monteiro, P; Coutinho, M; Salvador, MJ; Costa, ME; Malcata, AB

Objectives: To assess differences among health-related quality of life, pain threshold and perception, and passive coping strategies with chronic pain (specifically retreating, worrying, and resting), as well as associations among variables in three groups of rheumatic patients – fibromyalgia (FM), rheumatoid arthritis (RA), and osteoarthritis (OA). Material and methods: 86 participants diagnosed with FM (n = ...




Linfoma difuso de grandes células em doente com lúpus eritematoso sistémico

Duarte, C; Couto, M; Inês, L; Silva, J; Sousa, I; Malcata, AB

The authors present the case of a 44-year-old female patient with Systemic Lupus Erythematosus diagnosed 4 years earlier. She presented with constitutional symptoms and back pain and one month later a diagnosis of Non Hodgkin Lymphoma was established (subtype Diffuse Large B Cells Lymphoma). The risk of malignancy associated to SLE is discussed.


Artralgias, dores ósseas, anticorpos anti-nucleares positivos e trombocitopenia...

Ambrósio, C; Serra, S; Alexandre, M; Malcata, AB

The differential diagnosis of rheumatic diseases is sometimes very complex given the lack of specificity of some clinical manifestations. A careful physical examination with the aid of laboratory and radiographic findings can lead us to some rare conditions, reminding that they should never be forgotten in the differential diagnosis. The authors present a case report of a woman referred to the rheumatology depa...


Síndrome febril indeterminado em doente com dermatomiosite

Duarte, C; Monteiro, P; Serra, S; Salvador, MJ; Malcata, AB

The authors present a clinical case of a male, 54 year-old with the diagnosis of Dermatomyositis has 2 months ago. The patient, after a partial response to immunosuppressive therapy, presents with Fever of unknown origin. After a deep clinical evaluation it was established the diagnosis of resistant pulmonary tuberculosis. The differential diagnosis of fever of unknown origin in patients with dermatomyositis is...


Rash, fever and proteinuria after amoxicillin in a SLE patient

Couto, M; Duarte, C; Geraldes, A; Medeiros, C; Inês, L; Malcata, AB

We report a case of severe type IV hypersensitivity reaction to amoxicillin, which occurred in a person with a 12-year history of SLE. The present case illustrates the wide differential diagnosis in a SLE patient who presents with an allergic drug reaction. The attribution of the presenting symptoms to the underlying SLE and/or to the drugs used to treat SLE and coexisting conditions is a major challenge.


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