Data integration issues in the reconstruction of the genome-scale metabolic mod...

• Author(s): Pinto, José P. ; Dias, O. ; Lourenço, Anália ; Carneiro, S. ; Ferreira, E. C. ; Rocha, I. ; Rocha, Miguel
• Date: 2009
• Persistent ID: http://hdl.handle.net/1822/9067
• Origin: RepositóriUM - Universidade do Minho
• Subject(s): Genome-scale model reconstruction; Zymomonas mobillis; Data integration; Data quality
• Document Type: Part of book or chapter of book
• Language: English

Description

Genome-scale model reconstruction represents a major tool in the field of Metabolic Engineering .This paper reports on a study about data integration issues in the process of genome- scale reconstruction of the metabolic model of the bacterium Zymomonas mobilis, a promising organism for bioethanol production. Data is retrieved from the Entrez Gene, KEGG, BioCyc and Brenda databases, and the several processes involved in data integration from these sources are described, as well as the data quality issues.