Quantitative analysis of initial adhesion of bacterial vaginosis-associated ana...

• Author(s): Machado, António ; Salgueiro, Débora ; Harwich, Michael ; Jefferson, Kimberly K. ; Cerca, Nuno
• Date: 2013
• Persistent ID: http://hdl.handle.net/1822/25712
• Origin: RepositóriUM - Universidade do Minho
• Subject(s): Lactobacilli; Gardnerella vaginalis; Bacterial vaginosis; ME-180Vaginal epithelial cells
• Document Type: Article
• Language: English

Description

Bacterial vaginosis is the leading vaginal disorder but the transition from health to this dysbiotic condition remains poorly characterized. Our goal was to quantify the ability of BV-associated anaerobes to adhere to epithelial cells in the presence of lactobacilli. Gardnerella vaginalis outcompeted Lactobacillus crispatus and Lactobacillus iners actually enhanced its adherence.