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Quantitative analysis of initial adhesion of bacterial vaginosis-associated ana...
Machado, António; Salgueiro, Débora; Harwich, Michael; Jefferson, Kimberly K.; Cerca, NunoBacterial vaginosis is the leading vaginal disorder but the transition from health to this dysbiotic condition remains poorly characterized. Our goal was to quantify the ability of BV-associated anaerobes to adhere to epithelial cells in the presence of lactobacilli. Gardnerella vaginalis outcompeted Lactobacillus crispatus and Lactobacillus iners actually enhanced its adherence.
Quantitative analysis of initial adhesion of bacterial vaginosis anaerobes in M...
Machado, António; Salgueiro, Débora; Harwich, Michael; Jefferson, Kimberly K.; Cerca, NunoBacterial vaginosis (BV) is the most common vaginal disorder in women of reproductive age [1]. Despite decades of research, the etiology of BV still remains elusive. It is well established that adhesion to host cells or tissues is a necessary early step in the establishment of infection [2]. Since it is often considered a polymicrobial condition, it has been proposed that some bacteria have a preponderant role...
Detection of Lactobacillus and Gardnerella species in vaginal samples by PNA-FISH
Machado, António; Salgueiro, Débora; Almeida, Carina; Henriques, Ana Filipa; Haesebrouck, Freddy; Vaneechoutte, Mario; Rodrigues, L. R.; Cerca, NunoBacterial vaginosis (BV) is a common vaginal infection of women in reproductive age. This infection is initially asymptomatic and late diagnosis can increase the health costs and hamper treatment. Therefore, an easy and quick method to accurately detect the transition between normal microflora to the predecessors of infection is of upmost importance. Despite the fact that BV etiology remains unknown, it is comm...
O paradoxo da auto-prestação na era da abundância
Salgueiro, Débora Lídia Santos Mendonça PintoVive-se numa época transbordante de estímulos. O aumento da capacidade de produção em larga escala das organizações decorrente dos avanços tecnológicos, aliado à abertura de fronteiras, concede-nos uma dimensão de abundância e diversidade de bens de consumo desconhecida em outras épocas. Contrariamente ao que se tem verificado ao longo da História da vida humana, hoje, a oferta disponível de bens e serviços, na...
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