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Quantitative analysis of initial adhesion of bacterial vaginosis-associated ana...
Machado, António; Salgueiro, Débora; Harwich, Michael; Jefferson, Kimberly K.; Cerca, NunoBacterial vaginosis is the leading vaginal disorder but the transition from health to this dysbiotic condition remains poorly characterized. Our goal was to quantify the ability of BV-associated anaerobes to adhere to epithelial cells in the presence of lactobacilli. Gardnerella vaginalis outcompeted Lactobacillus crispatus and Lactobacillus iners actually enhanced its adherence.
Quantitative analysis of initial adhesion of bacterial vaginosis anaerobes in M...
Machado, António; Salgueiro, Débora; Harwich, Michael; Jefferson, Kimberly K.; Cerca, NunoBacterial vaginosis (BV) is the most common vaginal disorder in women of reproductive age [1]. Despite decades of research, the etiology of BV still remains elusive. It is well established that adhesion to host cells or tissues is a necessary early step in the establishment of infection [2]. Since it is often considered a polymicrobial condition, it has been proposed that some bacteria have a preponderant role...
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