Description
To evaluate the antifungal effect of gallic acid, catechin, luteolin and
quercetin, phenolic compounds identified from flowers of North Eastern Portugal, against
Candida planktonic and biofilm cells. Materials & methods: The MICs were determined in
Candida planktonic cells and the effect of phenolic compounds on Candida biofilms was
assessed through quantification of CFUs. Results: MIC values demonstrated that gallic acid
presented the highest effect against all Candida species. Catechin showed a similar effect
against Candida albicans American Type Culture Collection (ATCC) 90028 cells. In addition,
gallic acid and quercetin had demonstrated only a minimal effect against Candida species
biofilms. Conclusion: Gallic acid affected the growth of the different planktonic Candida
species in all concentrations used; still, catechin showed a similar effect against C. albicans
ATCC 90028 and Candida glabrata ATCC 2001 cells. In addition, only gallic acid and quercetin
demonstrated a slight effect against all Candida species biofilms.
; Ferreira, Isabel C.F.R. 
