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Mediterranean non-cultivated vegetables as dietary sources of compounds with an...
Morales, Patricia; Ferreira, Isabel C.F.R.; Carvalho, Ana Maria; Sánchez Mata, María de Cortés; Cámara Hurtado, Montaña; Fernández-Ruiz, VirginiaNon-cultivated vegetables whose basal leaves have been traditionally consumed in Spain were evaluated for their potential in human nutrition, considering vitamin C, organic acids, tocopherols, phenolics and flavonoids, and antioxidant activity. As far as we know, this is the first report on organic acids and vitamin C of Anchusa azurea and Apium nodiflorum, on tocopherols of Anchusa azurea, Beta vulgaris, Chond...
Effects of gamma irradiation on chemical composition and antioxidant potential ...
Ferrreira, Ângela; Barreira, João C.M.; Antonio, Amilcar L.; Oliveira, M.B.P.P.; Martins, Anabela; Ferreira, Isabel C.F.R.It was previously demonstrated that gamma irradiation was the processing technology with the highest capacity to maintain the chemical profile of fresh Macrolepiota procera wild mushroom, when compared to freeze-dried or oven-dried samples. Herein, it was aimed to evaluate gamma irradiation effects on processed samples. Chemical composition and antioxidant potential of irradiated (0.5 and 1 kGy) fresh, frozen a...
Chemical composition, antimicrobial, antioxidant and antitumor activity of Thym...
Nikolić, Miloš; Glamočlija, Jasmina; Ferreira, Isabel C.F.R.; Calhelha, Ricardo C.; Fernandes, Ângela; Marković, Tatjana; Marković, DejanAromatic plant species of genus Thymus are important medicinal plants, highly recommended due to a range of therapeutic properties of their essential oils, commonly known as thyme oil: antirheumatic, antiseptic, antispasmodic, antimicrobial, cardiac, carminative, diuretic and expectorant. The oil is also beneficial in boosting the immune system and helps to fight colds, flu, infectious diseases and chills. It i...
Cytotoxicity of Coprinopsis atramentaria extract, organic acids and their synth...
Heleno, Sandrina A.; Ferreira, Isabel C.F.R.; Calhelha, Ricardo C.; Esteves, Ana Paula; Martins, Anabela; Queiroz, Maria João R.P.Coprinopsis atramentaria is a wild edible mushroom whose methanolic extract revealed a marked antioxidant activity; p-hydroxybenzoic (HA), p-coumaric (CoA) and cinnamic (CA) acids were identified in the extract. In the present work, the cytotoxicity of C. atramentaria extract, previously identified organic acids and their synthesized derivatives (methylated compounds and protected glucuronides) was evaluated. A...
Synergisms in antioxidant and anti-hepatocellular carcinoma activities of artic...
Pereira, Carla; Calhelha, Ricardo C.; Barros, Lillian; Queiroz, Maria João R.P.; Ferreira, Isabel C.F.R.Artichoke, borututu and milk thistle are three medicinal plants well-known for their capacity to prevent oxidative stress and many liver diseases. In a previous work, we reported the bioactivity of infusions and pills based on these plants; herein, the aim was to provide scientific information about the antioxidant and anti-hepatocellular carcinoma activities of syrups based on these medicinal plants and evalua...
Development of a novel methodology for the analysis of ergosterol in mushrooms
Barreira, João C.M.; Oliveira, M.B.P.P.; Ferreira, Isabel C.F.R.Sterols are important molecules in the unsaponifiable fraction of several matrices. Ergosterol, which is an important vitamin D2 precursor, is clearly the main sterol in mushrooms. Herein, an analytical method for ergosterol determination in cultivated and wild mushrooms was developed using high-performance liquid chromatography coupled to ultraviolet detection. The chromatographic separation was achieved in an...
Exploring the antioxidant potential of Helichrysum stoechas (L.) Moench phenoli...
Barroso, Marisa; Barros, Lillian; Dueñas, Montserrat; Carvalho, Ana Maria; Santos-Buelga, Celestino; Fernandes, Isabel P.; Barreiro, M.F.The present work explores the antioxidant potential of Helichrysum stoechas (L.) Moench phenoliccompounds for cosmetic applications involving the following steps: chemical characterization, microen-capsulation and incorporation into a moisturizer. Eighteen different phenolic compounds were identifiedin flowering aerial parts (decoction and hydroalcoholic extract), being 3,5-O-dicaffeoylquinic acid andmyricetin ...
Ionizing radiation applications for a sustainable environment: food preservatio...
Antonio, Amilcar L.; Bento, Albino; Ferreira, Isabel C.F.R.; Cabo Verde, Sandra; Quintana, BegoñaThe use of ionizing gamma radiation is regulated and authorized by international organizations (EU, EFSA, IAEA, FAO, WHO) for industrial radiation processing of several products: medical devices sterilization, materials modification, cultural heritage preservation and food decontamination. Due to the wrong association of irradiated food with radioactive food, several obstacles have to be overcome in order to pr...
Docking studies in target proteins involved in mechanisms of antibacterial acti...
Alves, Maria José; Froufe, Hugo J.C.; Costa, Ana F.T.; Santos, Anabela F.; Oliveira, Liliana G.; Osório, Sara R.M.; Abreu, Rui M.V.; Pintado, ManuelaIn the present work, the knowledge on target proteins of standard antibiotics was extended to antimicrobial mushroom compounds. Docking studies were performed for 34 compounds in order to evaluate their affinity to bacterial proteins that are known targets for some antibiotics with different mechanism of action: inhibitors of cell wall synthesis, inhibitors of protein synthesis, inhibitors of nucleic acids synt...
Nutritional composition, antioxidant activity and phenolic compounds of wild Ta...
Dias, Maria Inês; Barros, Lillian; Alves, Rita C.; Oliveira, M.B.P.P.; Santos-Buelga, Celestino; Ferreira, Isabel C.F.R.Flowers and vegetative parts of wild Taraxacum identified as belonging to sect. Ruderalia were chemically characterized in nutritional composition, sugars, organic acids, fatty acids and tocopherols. Furthermore, the antioxidant potential and phenolic profiles were evaluated in the methanolic extracts, infusions and decoctions. The flowers gave higher content of sugars, tocopherols and flavonoids (mainly luteol...
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