Author(s):
Fernández, Ignacio 
; Cancela, Leonor ; Gavaia, Paulo J.
Date: 2012
Persistent ID: http://hdl.handle.net/10400.1/4350
Origin: Sapientia - Universidade do Algarve
Document details
Temporal and spatial expression patterns of pregnane X receptor and vitamin K e...
Description
Vitamin K (VK) is a liposoluble vitamin known to be essential for bone metabolism by two different pathways: (i) by its role as a coenzyme in the gamma-carboxylation of some skeletal proteins (e.g. osteocalcin (OC) and matrix Gla protein (MGP); Price et al., 1998); and (ii) through its role in skeletal gene transcription via binding to the pregnane X receptor (PXR; Azuma et al., 2010).
Vitamin K (VK) is a liposoluble vitamin known to be essential for bone metabolism by two different pathways: (i) by its role as a coenzyme in the gamma-carboxylation of some skeletal proteins (e.g. osteocalcin (OC) and matrix Gla protein (MGP); Price et al., 1998); and (ii) through its role in skeletal gene transcription via binding to the pregnane X receptor (PXR; Azuma et al., 2010).
Document Type
Conference Object
Language English
Language English
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