A systematic approach to the interrogation and sharing of standardised biofilm ...

• Autor(es): Lourenço, Anália ; Ferreira, Andreia ; Pereira, M. O. ; Azevedo, N. F.
• Data: 2012
• Identificador Persistente: http://hdl.handle.net/1822/24287
• Origem: RepositóriUM - Universidade do Minho
• Assunto(s): Infection-causing microorganisms; Biofilms; Legacy data; Data standardisation
• Tipo de Documento: Artigo
• Idioma: Inglês

Descrição

Publicado em "6th International Conference on Practical Applications of Computational Biology & Bioinformatics", ISBN 978-3-642-28838-8 The study of microorganism consortia, also known as biofilms, is associated to a number of applications in biotechnology, ecotechnology and clinical domains. A public repository on existing biofilm studies would aid in the design of new studies as well as promote collaborative and incremental work. However, bioinformatics approaches are hampered by the limited access to existing data. Scientific publications summarise the studies whilst results are kept in researchers’ private ad hoc files. Since the collection and ability to compare existing data is imperative to move forward in biofilm analysis, the present work has addressed the development of a systematic computer-amenable approach to biofilm data organisation and standardisation. A set of in-house studies involving pathogens and employing different state-of-the-art devices and methods of analysis was used to validate the approach. The approach is now supporting the activities of BiofOmics, a public repository on biofilm signatures (http://biofomics.org).