Fluorescence studies of potential antitumoral 6-heteroarylthieno[3,2-b]pyridine...

• Author(s): Carvalho, M. Solange D. ; Castanheira, Elisabete M. S. ; Oliveira, Andreia D. S. ; Calhelha, Ricardo C. ; Queiroz, Maria João R. P.
• Date: 2012
• Persistent ID: http://hdl.handle.net/1822/19952
• Origin: RepositóriUM - Universidade do Minho
• Subject(s): Antitumoral compounds; Fluorescence; Thieno[3,2-b]pyridines; Nanoliposomes
• Document Type: Conference Object
• Language: English

Description

Fluorescence properties of new potential antitumoral 6-heteroarylthieno[3,2-b]pyridines, recently synthesized, were studied in solution and in nanoliposomes of different compositions. The results indicate that these compounds can be transported in the hydrophobic region of the lipid bilayer. The liposomal formulation Egg-PC:Ch:DPPG (7:3:1) is the one with smaller size and lowest polydispersity.