Histological evaluation of the spleen after acute bleeding followed by volume r...

• Author(s): Cabral, M. ; Ortiz, A. ; Venâncio, C. ; Mesquita, J. ; Nóbrega, C. ; Silva, A. ; Vala, Helena ; Ferreira, D.
• Date: 2013
• Persistent ID: http://hdl.handle.net/10400.19/1898
• Origin: Repositório Científico do Instituto Politécnico de Viseu
• Subject(s): Spleen; Hemorrhagic shock; Physiological solutions; Hypovolemia; Hydroxyethyl Starch (HES); Ringer Lactate (RL); Acute controlled bleeding; Pig model
• Document Type: Conference Object
• Language: English

Description

Spleen is important for many hematopoietic and immunological functions, namely in hemodynamic compensation during hemorrhagic shock, with a crucial role in restoring blood volume in situations of acute haemorrhage. Also, the administration of physiological solutions is of great importance for the correction of circulating volume, avoiding complications due to hypovolemia. The aim of this study was to evaluate spleen`s histopathological changes, associated with volume replacement using two different physiologic solutions (Hydroxyethyl Starch (HES) 130/0.4 and Ringer Lactate), after acute controlled bleeding, in a pig model.