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Transition from cyclosporine-induced renal dysfunction to nephrotoxicity in an ...
Sereno, José; Rodrigues-Santos, Paulo; Vala, HelenaCyclosporin A (CsA), a calcineurin inhibitor, remain the cornerstone of immunosuppressive regimens, regardless of nephrotoxicity, which depends on the duration of drug exposure. The mechanisms and biomarkers underlying the transition from CsA-induced renal dysfunction to nephrotoxicity deserve better elucidation, and would help clinical decisions. This study aimed to clarify these issues, using a rat model of s...
Sitagliptin prevents aggravation of endocrine and exocrine pancreatic damage in...
Mega, Cristina; Vala, Helena; Rodrigues-Santos, Paulo; Oliveira, Jorge; Teixeira, Frederico; Fernandes, Rosa; Reis, Flávio; Lemos, Edite Teixeira deBackground: The purpose of this study was to investigate some of the possible mechanisms underlying the protective effects of a dipeptidyl peptidase IV (DPP-IV) inhibitor, sitagliptin, on pancreatic tissue in an animal model of type 2 diabetes mellitus (T2DM), the Zucker Diabetic Fatty (ZDF) rat, focusing on glycaemic, insulinic and lipidic profiles, as well as, on apoptosis, inflammation, angiogenesis and prol...
O papel do Enfermeiro Veterinário no acondicionamento e envio de amostras para ...
Vala, HelenaIn the present work, the main situations in which recourse to the laboratory is fundamental, are listed, as well as the main methods of taking samples from live animal and its execution. The main risks which compromise the quality and reliability of laboratory diagnosis, are related with incorrect methods of sampling, little information on their respective request records or its incorrect filled, also with fail...
Hormones and their Functions in the Dog. From the Cell to Hormone and from Horm...
Vala, Helena; Mesquita, J.; Esteves, F.; Cruz, R.; Mega, C.; Nóbrega, C.Animal bodies represent one of the more complex and perfect systems of nature but despite its complexity and functionality, the control of its basic functions is performed by only two systems: the nervous system and the endocrine system. Reproduction, gestation, muscle contraction, nutrient digestion and absorption, hydroelectrolytic balance, haematopoiesis and so many other bodily functions, are directly or in...
Doenças infeciosas felinas não zoonóticas
Vala, HelenaThe main feline infectious not zoonotic diseases include, among others, diseases of viral aetiology, including: - Feline panleukopenia caused by feline panleukopenia virus (FPV), from Parvoviridae family; - Feline infectious peritonitis (FIP), caused by feline infectious peritonitis virus (FIPV), a biotype of feline coronavirus (FCoV), Coronaviridae family; - The feline retroviruses, feline leukemia and feline ...
Canine and feline oral pathology
Costa, S.; Pais, B.; Almeida, D.; Simões, J.; Mega, A. C.; Vala, HelenaThe aim of this work was to present a brief review of the main conditions affecting the oral cavity of dogs and cats. In recent years there has been increased attention with regard to veterinary dentistry, being several and frequent the pathologies located in the oral cavity of our pets. These diseases mainly affect the teeth and the mucous membranes of the oral cavity, and may, in chronic cases, also affect vi...
Feline oral pathology
Costa, S.; Pais, B.; Almeida, D.; Simões, J.; Mega, A. C.; Vala, HelenaThe main pathologies of the oral cavity are of utmost importance, not only by the number of exposed individuals, but also by the consequences which stems. With the development of this work, we intend to conduct a brief approach to the same, since, specifically affecting domestic felines. Feline Lymphoplasmatic Gingivostomatitis (GELF), the Feline Odontoclastic Reabsorption Lesions (LROF) Complex and gingivitis-...
Nosocomial infections in veterinary
Delgado, A.; Delgado, A.; Ferreira, D.; Lopes, J.; Mesquita, J.; Vala, HelenaNosocomial infections (NIs) are acquired by patients during hospitalization (Nakamura & Tompkins, 2012), caused by an unbalance between the microbial flora and the patient's defense mechanism, or by the environment's colonization with pathogenic agents (Pereira et al., 2005). NIs are really important because they can cause serious consequences to the animal's health and well-being, worsen its primary condition ...
Relação causal da vacinação e o fibrossarcoma vacinal felino
Gonçalves, A.; Salas, C.; Nóbrega, C.; Cruz, R.; Esteves, F.; Santos, C.; Mega, A. C.; Santos, R.; Vala, HelenaOs Fibrossarcomas dos felinos domésticos estão reconhecidos desde há 10 anos e têm vindo a alertar os Veterinários, os proprietários e os fabricantes de vacinas, devido à possível ligação do acto de vacinação ao desenvolvimento deste sarcoma. A partir da década de 90, registou-se o aumento dos casos deste tumor na região cervical e interescapular dos gatos, locais frequentemente utilizados para a inoculação de ...
Cuidados de enfermagem em timpanismo
Oliveira, J.; Oliveira, J.; Rego, A.; Valente, A.; Nascimento, R.; Vala, Helena; Mesquita, J.; Nóbrega, C.O timpanismo ruminal designa-se pela acumulação excessiva de gases e por vezes fluidos no retículo-rúmen, incapazes de serem eliminados pelo organismo, o que resulta no aumento anormal do abdómen (Radostits et al, 2007). Afecta ruminantes e é uma situação que pode desenvolver-se rapidamente e pôr em risco a vida do animal (Streeter, 2009). Este estudo sintetiza a etiologia, o diagnóstico, o tratamento e aconsel...
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