A detailed comparative study between chemical and bioactive properties of Ganod...

• Author(s): Stojković, Dejan ; Barros, Lillian ; Calhelha, Ricardo C. ; Glamočlija, Jasmina ; Ćirić, Ana ; Van Griensven, Leo J.I.D. ; Soković, Marina ; Ferreira, Isabel C.F.R.
• Date: 2014
• Persistent ID: http://hdl.handle.net/10198/9865
• Origin: Biblioteca Digital do IPB
• Subject(s): Ganoderma lucidum; Chemical composition; Antioxidant activity; Cytotoxicity; Antimicrobial activity
• Document Type: Article
• Language: English

Description

A detailed comparative study on chemical and bioactive properties of wild and cultivated Ganoderma lucidum from Serbia (GS) and China (GCN) was performed. This species was chosen because of their worldwide use as medicinal mushroom. Higher amounts of sugars were found in GS, while higher amounts of organic acids were recorded in GCN. Unsaturated fatty acids predominated over saturated fatty acids. GCN revealed higher antioxidant activity, while GS exhibited inhibitory potential against human breast and cervical carcinoma cell lines. No cytotoxicity in non-tumour liver primary cell culture was observed for the different samples. Both samples possessed antibacterial and antifungal activities, in some cases even better than the standard antimicrobial drugs. This is the first study reporting a comparative of chemical compounds and bioactivity of G. lucidum samples from different origins.