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Chemical composition, antimicrobial, antioxidant and antitumor activity of Thym...

Nikolić, Miloš; Glamočlija, Jasmina; Ferreira, Isabel C.F.R.; Calhelha, Ricardo C.; Fernandes, Ângela; Marković, Tatjana; Marković, Dejan

Aromatic plant species of genus Thymus are important medicinal plants, highly recommended due to a range of therapeutic properties of their essential oils, commonly known as thyme oil: antirheumatic, antiseptic, antispasmodic, antimicrobial, cardiac, carminative, diuretic and expectorant. The oil is also beneficial in boosting the immune system and helps to fight colds, flu, infectious diseases and chills. It i...

Data: 2014   |   Origem: Biblioteca Digital do IPB

A detailed comparative study between chemical and bioactive properties of Ganod...

Stojković, Dejan; Barros, Lillian; Calhelha, Ricardo C.; Glamočlija, Jasmina; Ćirić, Ana; Van Griensven, Leo J.I.D.; Soković, Marina

A detailed comparative study on chemical and bioactive properties of wild and cultivated Ganoderma lucidum from Serbia (GS) and China (GCN) was performed. This species was chosen because of their worldwide use as medicinal mushroom. Higher amounts of sugars were found in GS, while higher amounts of organic acids were recorded in GCN. Unsaturated fatty acids predominated over saturated fatty acids. GCN revealed ...

Data: 2014   |   Origem: Biblioteca Digital do IPB

Two-dimensional PCA highlights the differentiated antitumor and antimicrobial a...

Dias, Maria Inês; Barreira, João C.M.; Calhelha, Ricardo C.; Queiroz, Maria João R.P.; Oliveira, M.B.P.P.; Soković, Marina; Ferreira, Isabel C.F.R.

Natural matrices are important sources of new antitumor and antimicrobial compounds. Species such as Laurus nobilis L. (laurel) might be used for this purpose, considering its medicinal properties. Herein, in vitro activity against human tumor cell lines, bacteria, and fungi was evaluated in enriched phenolic extracts. Specifically, methanol and aqueous extracts of wild and cultivated samples of L. nobilis were...

Data: 2014   |   Origem: Biblioteca Digital do IPB

Chemical characterization of the medicinal mushroom Phellinus linteus (Berkeley...

Reis, Filipa S.; Barreira, João C.M.; Calhelha, Ricardo C.; Van Griensven, Leo J.I.D.; Ćirić, Ana; Glamočlija, Jasmina; Soković, Marina

Mushrooms are widely appreciated for their organoleptic qualities, being also recognized as good sources of bioactive compounds that provide antioxidant, antimicrobial and cytotoxic activities. Polysaccharides (including glucans) are often pointed out as the most bioactive compounds isolated from mushrooms, but other molecules such as triterpenoids, might also be highlighted for their bioactivity. In scientific...

Data: 2014   |   Origem: Biblioteca Digital do IPB

Phenolic profiling of Veronica spp. grown in mountain, urban and sand soil envi...

Barreira, João C.M.; Dias, Maria Inês; Živković, Jelena; Stojković, Dejan; Soković, Marina; Santos-Buelga, Celestino; Ferreira, Isabel C.F.R.

Veronica (Plantaginaceae) genus is widely distributed in different habitats. Phytochemistry studies are increasing because most metabolites with pharmacological interest are obtained from plants. The phenolic compounds of V. montana, V. polita and V. spuria were tentatively identified by HPLC-DAD-ESI/MS. The phenolic profiles showed that flavones were the major compounds (V. montana: 7 phenolic acids, 5 flavone...

Data: 2014   |   Origem: Biblioteca Digital do IPB

Antimicrobial and cytotoxic activities of Alnus rugosa L. aerial partsand ident...

Rashed, Khaled N.; Ćirić, Ana; Glamočlija, Jasmina; Calhelha, Ricardo C.; Ferrreira, Isabel C.F.R.; Soković, Marina

This present investigation was undertaken to study antimicrobial and cytotoxic activities ofdichloromethane, ethyl acetate, and methanol 80% extracts from Alnus rugosa L. aerial parts, as wellinvestigate the bio-active compounds of each extract. Antimicrobial activity of the mentioned extractsagainst various bacteria and fungi using microdilution method, and cytotoxicity against five differenthuman tumor cell l...

Data: 2014   |   Origem: Biblioteca Digital do IPB

Cultivated strains of Agaricus bisporus and A. brasiliensis: chemical character...

Stojković, Dejan; Reis, Filipa S.; Glamočlija, Jasmina; Ćirić, Ana; Barros, Lillian; Van Griensven, Leo J.I.D.; Ferreira, Isabel C.F.R.; Soković, Marina

Agaricus bisporus (J. E. Lange) Emil J. Imbach and Agaricus brasiliensis Wasser, M. Didukh, Amazonas & Stamets are edible mushrooms. We chemically characterized these mushrooms for nutritional value, hydrophilic and lipophilic compounds. The antioxidant and antimicrobial activities of methanolic and ethanolic extracts were assessed. Hepatotoxicity was also evaluated. The ethanolic extract of both species was te...

Data: 2014   |   Origem: Biblioteca Digital do IPB

A comparative study of chemical composition, antioxidant and antimicrobial prop...

Heleno, Sandrina A.; Stojković, Dejan; Barros, Lillian; Glamočlija, Jasmina; Soković, Marina; Martins, Anabela; Queiroz, Maria João R.P.

A comparative study on chemical composition (nutritional value, primary and secondary metabolites), antioxidant properties (scavenging activity, reducing power and inhibition of lipid peroxidation), and antimicrobial activity (antibacterial and demelanizing properties) of two samples of Morchella esculenta (morel) from different countries (Portugal and Serbia) was performed. This species was chosen for being on...

Data: 2013   |   Origem: Biblioteca Digital do IPB

Antibacterial activity of Veronica montana L. extract and of protocatechuic aci...

Stojković, Dejan; Živković, Jelena; Soković, Marina; Glamočlija, Jasmina; Ferreira, Isabel C.F.R.; Janković, Teodora; Maksimović, Zoran

This study was designed to evaluate the antibacterial activity of the Veronica montana L. water extract and its main phenolic compound, protocatechuic acid. The antibacterial activity was determined by microdilution assay against six strains of Gram-positive and Gram-negative bacteria. Listeria monocytogenes was the most sensitive of the tested bacterial species. Antibacterial preserving properties of protocate...

Data: 2013   |   Origem: Biblioteca Digital do IPB

Tirmania pinoyi: chemical composition, in vitro antioxidant and antibacterial a...

Stojković, Dejan; Reis, Filipa S.; Ferreira, Isabel C.F.R.; Barros, Lillian; Glamočlija, Jasmina; Ćirić, Ana; Nikolić, Miloš; Stević, Tanja

Desert truffle, Tirmania pinoyi (Maire) Malençon from Libya was chemically characterized in nutritional value, primary and secondary metabolites. Antioxidant (scavenging activity, reducing power and inhibition of lipid peroxidation) and antibacterial activity of its methanolic extract alone and in combination with potassium metabisulfite (E224) were evaluated under in vitro conditions. Furthermore, the effect o...

Data: 2013   |   Origem: Biblioteca Digital do IPB

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    Financiadores do RCAAP

Fundação para a Ciência e a Tecnologia Universidade do Minho   Governo Português Ministério da Educação e Ciência Programa Operacional da Sociedade do Conhecimento União Europeia