Evaluation of the antioxidant properties of diarylamines in the benzo[b]thiophe...

• Author(s): Ferreira, Isabel C.F.R. ; Queiroz, Maria João R.P. ; Vilas-Boas, Miguel ; Estevinho, Leticia M. ; Begouin, Agathe ; Kirsch, Gilbert
• Date: 2006
• Persistent ID: http://hdl.handle.net/10198/825
• Origin: Biblioteca Digital do IPB
• Subject(s): Diarylamines; Benzothiophenes; Antioxidant activity; Structure–activity relationships
• Document Type: Article
• Language: English

Description

The antioxidant properties of substituted diarylamines in the benzo[b]thiophene series were evaluated by their reducing power and free radical scavenging activity. The results were compared with those of standards: acid ascorbic for the first method and BHA and BHT for the second. For both methods it was possible to establish some structure–activity relationships (SARs) based on the position of the arylamination on the benzo[b]thiophene moiety, the presence of different substituents on the phenyl ring (F, 1 or 2 OMe) and on the thiophene ring (H, CO2Et, CO2H).