Intermolecular alkyl radical addition to methyl 2-(2,6-Dichlorophenyl)-2H-aziri...

• Author(s): Lemos, A. ; Guimaraes, Emanuel ; Fortes, Gil ; Alves, Maria José Chão
• Date: 2003
• Persistent ID: http://hdl.handle.net/10400.1/1023
• Origin: Sapientia - Universidade do Algarve
• Subject(s): Azirinas; Heterocycles; Intermolecular radical addition; Triethylborane; Alfa-aminoesters
• Document Type: Article
• Language: English

Description

The 2H-azirine 1 acts as an effective radical acceptor for secondary and tertiary alkyl iodides mediated by triethylborane. The addition proceeds with high regio- and diastereo-selectivity.