A propósito de um caso de espessamento cutâneo

• Author(s): Serra, S ; Ambrósio, C ; Salvador, MJ ; Silva, J ; Serra, D ; Reis, JP ; Malcata, AB
• Date: 2010
• Persistent ID: http://hdl.handle.net/10400.4/905
• Origin: Repositório do Centro Hospitalar e Universitário de Coimbra
• Subject(s): Escleromixedema; Pele
• Document Type: Article
• Language: Portuguese

Description

The authors present a clinical case of a 79 years old female patient, with a progressive cutaneous thickening of the face, trunk and limbs, lasting for 6 years. She also presented exertional dyspnea and intermittent solid dysphagia. The laboratory study identified IgG KAPA monoclonal protein and antinuclear antibodies with a speckled pattern. The nailfold capillaroscopy was normal. A detailed physical examination together with cutaneous histopathology led to the diagnosis of Scleromyxedema, a rare cutaneous scleroderma like disease. The differential diagnosis of cutaneous sclerosis is discussed.