Safety of low dose glucocorticoid treatment in rheumatoid arthritis: published ...

• Author(s): Pereira da Silva, JA ; Jacobs, JW ; Kirwan, JR ; Boers, M ; Saag, KG ; Inês, L ; Koning, EJ
• Date: 2006
• Persistent ID: http://hdl.handle.net/10400.4/204
• Origin: Repositório do Centro Hospitalar e Universitário de Coimbra
• Subject(s): Artrite Reumatóide; Glucocorticóides; Medicina Baseada na Evidência; Anti-Reumáticos
• Document Type: Article
• Language: English

Description

Adverse effects of glucocorticoids have been abundantly reported. Published reports on low dose glucocorticoid treatment show that few of the commonly held beliefs about their incidence, prevalence, and impact are supported by clear scientific evidence. Safety data from recent randomised controlled clinical trials of low dose glucocorticoid treatment in RA suggest that adverse effects associated with this drug are modest, and often not statistically different from those of placebo.