Pityriasis lichenoides et varioliformis acute: case report and review of the li...

• Author(s): Pereira, N ; Brinca, A ; Brites, MM ; Julião, MJ ; Tellechea, O ; Gonçalo, Margarida
• Date: 2012
• Persistent ID: http://hdl.handle.net/10400.4/1430
• Origin: Repositório do Centro Hospitalar e Universitário de Coimbra
• Subject(s): Pitiríase Liquenóide
• Document Type: Article
• Language: English

Description

We report a case of a 63-year-old man hospitalized for a polymorphous generalized eruption consisting of maculopapules with peripheral scaling, vesicopustules, and ulceronecrotic and crusted lesions measuring 5-20 mm, localized on his trunk and extremities, particularly exuberant in the flexural area. Histopathology showed necrotic keratinocytes with exocytosis of red blood cells and lymphocytes and a dermal perivascular and periadnexal inflammatory infiltrate, composed of CD8+/CD4-/CD30- T cells, indicating the clinical diagnosis of pityriasis lichenoides et varioliformis acuta. He was treated with erythromycin and methylprednisolone reduced gradually over 5 months, with a slow but complete response; the patient was without lesions after 2 years of follow-up. The authors want to remind of this rare entity which may present difficulties in diagnosis and therapy