Sensitivity analysis in a dengue epidemiological model

• Author(s): Rodrigues, Helena Sofia ; Monteiro, M. Teresa T. ; Torres, Delfim F. M.
• Date: 2013
• Persistent ID: http://hdl.handle.net/1822/25133
• Origin: RepositóriUM - Universidade do Minho
• Subject(s): Sensitivity analysis; Basic reproduction number; Epidemiological model; Dengue
• Document Type: Conference Object
• Language: English

Description

Epidemiological models may give some basic guidelines for public health practitioners, allowing the analysis of issues that can influence the strategies to prevent and fight a disease. To be used in decision making, however, a mathematical model must be carefully parameterized and validated with epidemiological and entomological data. Here an SIR (S for susceptible, I for infectious, and R for recovered individuals) and ASI (A for the aquatic phase of themosquito, S for susceptible, and I for infectiousmosquitoes) epidemiological model describing a dengue disease is presented, as well as the associated basic reproduction number. A sensitivity analysis of the epidemiological model is performed in order to determine the relative importance of the model parameters to the disease transmission.