DNA fluorescence probes based on side-chain chlorinated benzo[a]phenoxazinium c...

• Author(s): Raju, B. Rama ; Firmino, A. D. G. ; Gonçalves, M. Sameiro T. ; Coutinho, Paulo J. G.
• Date: 2012
• Persistent ID: http://hdl.handle.net/1822/21593
• Origin: RepositóriUM - Universidade do Minho
• Subject(s): DNA probes; Fluorescence; Benzo[a]phenoxazine dyes
• Document Type: Conference Object
• Language: English

Description

Several side chain chlorinated benzo[a]phenoxazinium chlorides functionalized with various types of terminals at the 5- and 9-amino positions of the heteroaromatic ring were used in photophysical studies with DNA. It was found that the functionalised terminal has a dramatic influence on the type of interaction with the amino group at the 9-amino position greatly promoting intercalation.