Synthesis of novel derivatives of 4-amino-3,5-dicyanopyrazole

• Author(s): Campos, Ana M. F. Oliveira ; Gonçalves, M. Sameiro T. ; Rodrigues, Lígia M. ; Proença, M. Fernanda R. P. ; Griffiths, John ; Maia, Hernâni L. S. ; Kaja, Martin ; Hrdina, Radim
• Date: 2004
• Persistent ID: http://hdl.handle.net/1822/1246
• Origin: RepositóriUM - Universidade do Minho
• Subject(s): Pyrazole; Dicyanopyrazole
• Document Type: Article
• Language: English

Description

Diazotisation of substituted arylamines followed by reaction with malononitrile gave substituted arylazomalononitriles. Cyclisation of these intermediates with chloroacetonitrile and triethylamine, as base, gave the corresponding new aminodicyanopyrazoles, in 22–80% yields.