Desacyl-ghrelin does not influence insulin sensitivity

• Autor(es): Veiga, Luísa ; Brito, Miguel ; Oliveira, Ana ; Silva-Fortes, Carina ; Silva-Nunes, José
• Data: 2014
• Identificador Persistente: http://hdl.handle.net/10400.21/3867
• Origem: Repositório Científico do Instituto Politécnico de Lisboa
• Assunto(s): Insulin sensitivity; Obesity; Adiposity; Diabetes; Acyl-ghrelin; Food intake; Metabolism
• Tipo de Documento: Documento de conferência
• Idioma: Inglês

Descrição

Acyl-ghrelin has been reported to increase food intake and adiposity and it is the best studied of the orexigenic gastrointestinal hormones. On the other hand, desacyl-ghrelin – DAG (the unacylated form of the hormone) has been reported as a potential player on carbohydrate metabolism. However, the potential impact of DAG on glucose homeostasis remains uncertain. In this study we aim to assess the association between DAG and insulin sensitivity.