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Thyroid carcinoma in children and young adults: retrospective review of 19 cases

Introduction: Thyroid carcinoma is rare in children and young adults. Most of management guidelines are based in data from adult population. Several controversies remain regarding the aggressiveness of clinical presentation and therapeutic approach. Objective: To evaluate all differentiated thyroid carcinoma patients with less than 20 years-old at presentation reflecting the experience of our unit in relation t...

Variability over time in the sources of South Portuguese Zone turbidites: evide...

This study combines geochemical and geo- chronological data in order to decipher the provenance of Carboniferous turbidites from the South Portuguese Zone (SW Iberia). Major and trace elements of 25 samples of graywackes and mudstones from the Me´rtola (Visean), Mira (Serpukhovian), and Brejeira (Moscovian) Forma- tions were analyzed, and 363 U-Pb ages were obtained on detrital zircons from five samples of gray...

Osteoblast, fibroblast and in vivo biological response to poly(vinylidene fluorid...

Electroactivematerials can be taken to advantage for the development of sensors and actuators as well as for novel tissue engineering strategies. Composites based on poly(vinylidenefluoride),PVDF,have been evaluated with respect to their biological response. Cell viability and proliferation were performed in vitro both with Mesenchymal Stem Cells differentiated to osteoblasts and Human Fibroblast Foreskin 1. In ...

PHB-PEO electrospun fiber membranes containing chlorhexidine for drug delivery ...

Fiber meshes of poly(hydroxybutyrate) (PHB) and poly(hydroxybutyrate)/ poly(ethylene oxide) (PHB/PEO) with different concentrations of chlorhexidine (CHX) were prepared by electrospinning, for assessment as a polymer based drug delivery system. The electrospun fibers were characterized at morphological, molecular and mechanical levels. The bactericidal potential of PHB and PHB/PEO electrospun fibers with and wi...

Effect of filler content on morphology and physical-chemical characteristics of...

Poly(vinylidene fluoride) electrospun membranes have been prepared with different NaY zeolite contents up to 32%wt. Inclusion of zeolites induces an increase of average fiber size from ~200 nm in the pure polymer up to ~500 nm in the composite with 16%wt zeolite content. For higher filler contents, a wider distribution of fibers occurs leading to a broader size distributions between the previous fiber size valu...

Bioactive albumin functionalized polylactic acid membranes for improved biocomp...

Biocompatibility is a major challenge for successful application of many biomaterials. In this study the ability to coat chemically and enzymatically activated poly(L-lactic acid) (PLA) membranes with heat denatured human serum albumin to improve biocompatibility was investigated. PLA membranes hydrolyzed with NaOH or cutinase and then treated with 1-ethyl-3-(3-dimethylaminopropyl)carbodiimide, hydrochloride (E...

A Bacia do Algarve : estratigrafia, paleogeografia e tectónica

Controlo de qualidade: a cereja no topo do bolo

Prémio da Melhor Comunicação Oral ; Introdução: As metodologias de controlo interno de qualidade são uma exigência dos sistemas de certificação e acreditação de laboratórios. A discussão/divulgação deste tipo de ferramentas no contexto da anatomia patológica facilitaria a sua implementação na rotina laboratorial, constituindo um desafio para todos os profissionais. Objectivos: Elaborar uma ferramenta de contr...

TIRADS e a lesão folicular de significado indeterminado (LFSI) da tiróide

Prémio do "Melhor Poster" das 8ªs Jornadas. ; Objectivos: Avaliar o papel da classificação Thyroid Imaging Reporting and Data System (TIRADS) da ecografia da tiróide, nos nódulos da categoria Lesão Folicular de Significado Indeterminado (LFSI ) do Sistema de Bethesda. Materiais e métodos: Estudo retrospectivo, entre Janeiro de 2011 e Agosto de 2013, a um total de 40 nódulos tiroideus submetidos a citologia asp...

Conhecimento e formação de futuros professores dos primeiros anos – o sentido d...

Nos últimos anos o conhecimento do professor tem vindo a ser reconhecido como um dos aspetos nucleares no, e para o, desenvolvimento do conhecimento matemático dos alunos. Atendendo a essa centralidade, a formação deverá focar-se onde é, efetivamente, necessária, de modo a potenciar um incremento do conhecimento dos alunos, pelo conhecimento (e práticas) dos professores. Sendo os números racionais um dos tópico...