Encontrados 9 documentos, a visualizar página 1 de 1
Glucose-6-Phosphate dehydrogenase deficiency in children from 0 to 14 years hos...
Brito, Miguel; Tchonhi, Chissengo Lucama; Santos, Brígida; Veiga, LuísaThe Glucose-6-phosphate dehydrogenase (G6PD) deficiency is the most common enzymatic defect in the world. The most common clinical manifestations are acute hemolytic anemia associated with drugs, infections, neonatal jaundice and hemolytic non-spherocytic chronic anemia. The main aim of this study was to determine the frequency of major genetic variants of G6PD leading to enzyme deficiency in children from 0 to...
Desacyl-ghrelin does not influence insulin sensitivity
Veiga, Luísa; Brito, Miguel; Oliveira, Ana; Silva-Fortes, Carina; Silva-Nunes, JoséAcyl-ghrelin has been reported to increase food intake and adiposity and it is the best studied of the orexigenic gastrointestinal hormones. On the other hand, desacyl-ghrelin – DAG (the unacylated form of the hormone) has been reported as a potential player on carbohydrate metabolism. However, the potential impact of DAG on glucose homeostasis remains uncertain. In this study we aim to assess the association b...
Factors related with adiponectinemia in obese and normal-weight women and with ...
Silva-Nunes, José; Oliveira, Ana; Duarte, Leone; Barradas, Margarida; Melão, Alice; Brito, Miguel; Veiga, LuísaObjective: To assess different factors influencing adiponectinemia in obese and normal-weight women; to identify factors associated with the variation (Δ) in adiponectinemia in obese women following a 6-month weight loss program, according to surgical/non-surgical interventions. Methods: We studied 100 normal-weight women and 112 obese premenopausal women; none of them was on any medical treatment. Women were c...
Occupational exposure to Aflatoxin B1 in Portuguese swine farms
Viegas, Susana; Veiga, Luísa; Figueiredo, Paula; Almeida, Ana; Carolino, Elisabete; Viegas, CarlaAflatoxins were first isolated about 40 years ago afier outbreaks of disease and death in turkeys and cancer in rainbow trout fed with rations formulated from peanut and cottonseed meals. These toxins are secondary metabolites produced under certain conditions of temperature, p14 and humidity predominantiy by Aspergilius flavus and Aspergilius parasiticus fungi species. Among 18 different types of aflatoxins id...
Association of FTO and PPARG polymorphisms with obesity in Portuguese women
Carlos, Fábio Ferreira; Silva-Nunes, José; Flores, Orfeu; Brito, Miguel; Doria, Gonçalo; Veiga, Luísa; Baptista, Pedro VianaPurpose: We evaluated the association between risk of obesity in the Portuguese population and two obesity-related single-nucleotide gene polymorphisms: fat-mass and obesity-associated (FTO) rs9939609 and peroxisome proliferator-activated receptor gamma (PPARG) rs1801282. Patients and methods: A total of 194 Portuguese premenopausal female Caucasians aged between 18 and 50 years (95 with body mass index [BMI] ≥...
Automonitorização e programação de contingências numa intervenção para perda de...
Veiga, Luísa, 1961-Tese de mestrado, Psicologia (Secção de Psicologia Clínica e da Saúde - Núcleo de Psicologia da Saúde e da Doença), Universidade de Lisboa, Faculdade de Psicologia, 2012 ; A presente investigação teve como objectivo principal contribuir para a melhor compreensão dos factores de adesão/sucesso a um tratamento para perda de peso, tendo por orientação o modelo construtivista-desenvolvimentista de Joyce-Moniz (199...
Occupational exposure to aflatoxin (AFB1) in poultry production
Viegas, Susana; Veiga, Luísa; Malta-Vacas, Joana; Sabino, Raquel; Figueiredo, Paula; Almeida, Ana; Viegas, CarlaAflatoxin B1 (AFB1) has been recognized to cause cancer in the humans liver. Epidemiological and laboratory evidence also point towards the respiratory system as target for carcinogenesis. Exposure occurs mainly through food chain but inhalation represent an additional route of exposure. Agricultural workers have the greatest risk of occupational exposure due to their exposition to airborne aflatoxin through in...
Biological monitoring of aflatoxin (AFB1) in workers of swine and poultry produ...
Viegas, Susana; Veiga, Luísa; Almeida, Ana; Figueiredo, Paula; Carolino, Elisabete; Viegas, CarlaAlthough a great body of literature exists concerning the ingestion of food contaminated with aflatoxin, there are still few studies regarding mycotoxin inhalation in occupational settings. Since mycotoxins are relatively non-volatile, inhalation exposure is cause by inhalation of airborne fungal particulates or fungi-contaminated substrates that contain aflatoxin. We intend to know if there is occupational exp...
Q192R polymorphism of the paraoxonase-1 gene as a risk factor for obesity in Po...
Veiga, Luísa; Silva-Nunes, José; Melão, Alice; Oliveira, Ana; Duarte, Leone; Brito, MiguelIntroduction - Obesity became a major public health problem as a result of its increasing prevalence worldwide. Paraoxonase-1 (PON1) is an esterase able to protect membranes and lipoproteins from oxidative modifications. At the PON1 gene, several polymorphisms in the promoter and coding regions have been identified. The aims of this study were i) to assess PON1 L55M and Q192R polymorphisms as a risk factor for ...
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