Desacyl-ghrelin does not influence insulin sensitivity

• Author(s): Veiga, Luísa ; Brito, Miguel ; Oliveira, Ana ; Silva-Fortes, Carina ; Silva-Nunes, José
• Date: 2014
• Persistent ID: http://hdl.handle.net/10400.21/3867
• Origin: Repositório Científico do Instituto Politécnico de Lisboa
• Subject(s): Insulin sensitivity; Obesity; Adiposity; Diabetes; Acyl-ghrelin; Food intake; Metabolism
• Document Type: Conference Object
• Language: English

Description

Acyl-ghrelin has been reported to increase food intake and adiposity and it is the best studied of the orexigenic gastrointestinal hormones. On the other hand, desacyl-ghrelin – DAG (the unacylated form of the hormone) has been reported as a potential player on carbohydrate metabolism. However, the potential impact of DAG on glucose homeostasis remains uncertain. In this study we aim to assess the association between DAG and insulin sensitivity.