Document details

Adult nesidioblastosis.

Author(s): Branco, Vítor A cv logo 1 ; Santos, Rui M cv logo 2 ; Cipriano, M Augusta cv logo 3 ; Tralhão, Guilherme cv logo 4 ; Otero, M cv logo 5 ; Moura, José A cv logo 6 ; Sousa, F Castro cv logo 7 ; Porto, Armando cv logo 8

Date: 2003

Origin: Acta Médica Portuguesa


Description
In adults, endogenous hyperinsulinemic hypoglycaemia is almost invariably due to insulinoma. The authors describe a 29 year old patient with repeated postprandial symptomatic hypoglycaemias and negative prolonged fast test. Distal pancreatectomy was performed, directed by positive arteriographic testing. Histological examination revealed pancreatic nesidioblastosis and no tumoral lesion. Distinct pathogenetic, clinical, diagnostic and therapeutic aspects of this rare disease in the adult are reviewed. In adults, endogenous hyperinsulinemic hypoglycaemia is almost invariably due to insulinoma. The authors describe a 29 year old patient with repeated postprandial symptomatic hypoglycaemias and negative prolonged fast test. Distal pancreatectomy was performed, directed by positive arteriographic testing. Histological examination revealed pancreatic nesidioblastosis and no tumoral lesion. Distinct pathogenetic, clinical, diagnostic and therapeutic aspects of this rare disease in the adult are reviewed.
Document Type Article
Language Portuguese
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