Electrochemical oxidation of ochratoxin A at a glassy carbon electrode and in s...

• Author(s): Oliveira, S. C. B. ; Diculescu, V. C. ; Palleschi, G. ; Compagnone, D. ; Oliveira-Brett, A. M.
• Date: 2007
• Persistent ID: http://hdl.handle.net/10316/5048
• Origin: Estudo Geral - Universidade de Coimbra
• Subject(s): Ochratoxin A; Deoxyribonucleic acid; Oxidative damage; Oxidation; Voltammetry; Electroanalytical determination; Interferences
• Document Type: Article
• Language: English

Description

Ochratoxin A (OTA) is a fungal metabolite that occurs in foods, beverages, animal tissues, human blood and presents carcinogenic, teratogenic and nephrotoxic properties. This study concerns the redox properties of OTA using electrochemical techniques which have the potential for providing insights into the biological redox reactions of this molecule. The in situ evaluation of the OTA interaction with DNA using a DNA-electrochemical biosensor is also reported. http://www.sciencedirect.com/science/article/B6TF4-4N3GFN7-3/1/57e4418b7a355b04b0c0ad5eec1834e7