Drug delivery: from a contact lens to the anterior chamber

• Author(s): Ferreira, J. A. ; Oliveira, P. de ; Silva, P. M. da ; Murta, J. N.
• Date: 2010
• Persistent ID: http://hdl.handle.net/10316/13704
• Origin: Estudo Geral - Universidade de Coimbra
• Subject(s): Ophthalmic contact lens; Nanoparticles; Polymeric matrix; Cornea; Anterior chamber; Diffusion
• Document Type: Preprint
• Language: English

Description

Mathematical models to describe drug concentration profiles of topically administered drug in the anterior chamber aqueous humor have been proposed by several authors. The aim of this paper is to present a mathematical model to predict the drug concentration in the anterior chamber when a therapeutical contact lens with the drug is entrapped in nanoparticles is used.