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Flux Tracking in delivery polymeric systems

The dynamics of diffusive and stress-induced transport in polymeric delivery systems was investigated. Partial and ordinary differential equations were first written to describe drug release behaviors in Maxwell and Maxwell-Voigt materials. The time constants governing the flux and concentration responses of a permeating species were determined from a Laplace transform solution of the original model. A ”trackin...

Drug delivery: from a contact lens to the anterior chamber

Mathematical models to describe drug concentration profiles of topically administered drug in the anterior chamber aqueous humor have been proposed by several authors. The aim of this paper is to present a mathematical model to predict the drug concentration in the anterior chamber when a therapeutical contact lens with the drug is entrapped in nanoparticles is used.

Sustained drug released from contact lens

This paper focuses on ophthalmic drug release from a loaded copolymer: the drug is dispersed in the polymeric matrix and entrapped in particles. The copolymer is based in 2-hydroxyethyl methacrylate co-methacrylic acid and silicone is used to prepare the loaded particles. A mathematical model to simulate the drug release is proposed and a qualitative analysis is performed. Experimental results are compared with...

Estudo colaborativo gaúcho de glomerulopatias : resultados iniciais

Structural and magnetic characterization of Ni nanoparticles synthesized in ion...

Energy estimates for delay diffusion-reaction equations

In this paper we consider nonlinear delay diffusion-reaction equations with initial and Dirichlet boundary conditions. The behavior and the stability of the solution of such initial boundary value problems (IBVPs) are studied using energy method. Simple numerical methods are considered on the computation of numerical approximations to the solution of the nonlinear IBVPs. Using the discrete energy method we stud...

EFEITOS DO EXTRATO AQUOSO DA HYPTIS PECTINATA SOBRE A REGENERAÇÃO HEPÁTICA APÓS...

O uso de plantas medicinais tem aumentado bastante na população mundial. O objetivo desta pesquisa é avaliar os efeitos do extrato aquoso das folhas da Hyptis pectinata, popularmente conhecida como "sambacaitá" ou "canudinho", sobre a regeneração hepática após hepatectomia parcial de 70%. Foram utilizados 24 ratos, divididos em 4 grupos: grupo OS, em que se realizou operação simulada e aplicação oral de água de...