Accuracy of prenatal culture in predicting intrapartum group B streptococcus co...

• Author(s): Florindo, C ; Damião, V ; Lima, J ; Nogueira, I ; Rocha, I ; Caetano, P ; Ribeiro, L ; Viegas, S ; Gomes, JP ; Borrego, MJ
• Date: 2014
• Origin: Repositório Comum
• Subject(s): Pregnancy Complications, Infectious; Streptococcal Infections; Infectious Disease Transmission, Vertical; Infecções por Estafilocócos; Complicações Infecciosas na Gravidez; Transmissão Vertical de Doença Infecciosa
• Document Type: Article
• Language: English

Description

OBJECTIVE: To evaluate the positive predictive value (PPV) of group B Streptococcus (GBS) cultures at 35-37 weeks of gestation relative to GBS colonization status at delivery. METHODS: Rectovaginal swabs from 221 women at labor in four Lisbon hospitals were collected for GBS screening according to the CDC guidelines. RESULTS: The PPV was 24.4%. IAP was administered to 100% of prenatally GBS positive women. There was no case of early onset GBS disease (EOD). CONCLUSIONS: Poor accuracy of prenatal cultures in identifying true candidates for IAP highlights the need for Portuguese clinical and laboratory guidelines to prevent EOD and antibiotic overtreatment of pregnant women.