Palladium-catalyzed amination and cyclization to heteroannellated indoles and c...

• Author(s): Ferreira, Isabel C.F.R. ; Queiroz, Maria João R.P. ; Kirsch, Gilbert
• Date: 2003
• Persistent ID: http://hdl.handle.net/10198/817
• Origin: Biblioteca Digital do IPB
• Subject(s): Palladium; Amination; Ortho-bromodiarylamines; Cyclization
• Document Type: Article
• Language: English

Description

New ortho-bromodiarylamines in the benzo[b]thiophene series were prepared by palladium-catalyzed amination, either in the benzene or in the thiophene ring. These were submitted to palladium-catalyzed cyclization, under different required conditions, to give several differently substituted thieno[3,2-c] or [2,3-b]carbazoles and indolo[3,2-b]benzo[b]thiophenes. This constitutes a novel synthetic route to both tetracyclic systems