Confocal micro-PIV/PTV measurements of the blood flow in micro-channels

• Author(s): Lima, R. ; Ishikawa, T. ; Imai, Y. ; Yamaguchi, T.
• Date: 2013
• Persistent ID: http://hdl.handle.net/10198/10383
• Origin: Biblioteca Digital do IPB
• Subject(s): Micro-channels; Blood flow; Red blood cells; Micro-PIV/PTV
• Document Type: Part of book or chapter of book
• Language: English

Description

The development of optical experimental techniques has contributed to obtain explanations on the blood flow behaviour through micro-channels. Although the past results have been valuable, detailed studies on the flow properties of in vitro blood in micro-channels have been limited by several technical factors such as poor spatial resolution and difficulty to obtain quantitative detailed meas-urements at such small scales. In recent years, due to advances in computers, op-tics, and digital image processing techniques, it became possible to combine both particle image velocimetry (PIV) and particle tracking velocimetry (PTV) methods with confocal microscopes. As a result, this combination has greatly increased the resolution of the conventional micro-PIV/PTV systems and consequently pro-vided additional detailed description on the blood cells motion not obtainable by traditional methods. In this chapter the most relevant theoretical and technical is-sues related to both conventional and confocal micro-PIV/PTV methods are dis-cussed. In addition, a comparison between them is presented. Furthermore, the most relevant results of in vitro blood flowing in both glass and polydime-thylsiloxane (PDMS) micro-channels are shown.