Encontrados 21 documentos, a visualizar página 1 de 3
Amplified and Homozygously Deleted Genes in Glioblastoma: Impact on Gene Expres...
Crespo, I; Tão, H; Nieto, AB; Rebelo, O; Domingos, P; Vital, AL; Patino, MC; Barbosa, MD; Lopes, MC; Resende de Oliveira, C; Orfão, A; Tabernero, MDBACKGROUND: Glioblastoma multiforme (GBM) displays multiple amplicons and homozygous deletions that involve relevant pathogenic genes and other genes whose role remains unknown. METHODOLOGY: Single-nucleotide polymorphism (SNP)-arrays were used to determine the frequency of recurrent amplicons and homozygous deletions in GBM (n = 46), and to evaluate the impact of copy number alterations (CNA) on mRNA levels of...
Numerical analysis of piping elbows for in-plane bending and internal pressure
Fonseca, E.M.M.; Melo, F.J.M.Q. de; Oliveira, C.A.M deThis work presents the development of two different finite piping elbow elements with two nodal tubular sections for mechanical analysis. The formulation is based on thin shell displacement theory, where the displacement is based on high-order polynomial or trigonometric functions for rigid-beam displacement, and uses Fourier series to model warping and ovalization phenomena of cross-tubular section. To model t...
Trigonometric function used to formulate a multi-nodal finite tubular element
Fonseca, E.M.M.; Melo, F.J.M.Q. de; Oliveira, C.A.M deIt is presented an alternative formulation to solve the problem of the deformation analysis for tubular element under pinching loads. The solution is based on a new displacement field defined from a total set of trigonometric functions. The solution is developed in a multi-nodal finite tubular ring element with a total of eight degrees of freedom per section considered. The purpose of this paper is to provide a...
Pathologic study of a fatal case of dengue-3 virus infection in Rio de Janeiro,...
Basílio-de-Oliveira,C.A.; Aguiar,G.R.; Baldanza,M.S.; Barth,O.M.; Eyer-Silva,W.A.; Paes,M.V.Dengue hemorrhagic fever (DHF) is a severe febrile disease, characterized by abnormalities in hemostasis and increased vascular permeability, which in some cases results in hypovolemic shock syndrome and in dengue shock syndrome. The clinical features of DHF include plasma leakage, bleeding tendency and liver involvement. We studied the histopathological features of a fatal case of dengue-3 virus infection. The...
The thermal and mechanical behaviour of structural steel piping systems
Fonseca, E.M.M.; Melo, F.J.M.Q. de; Oliveira, C.A.M deThe temperature, the deformation and the stress field in thermo-mechanical problems play a very important role in engineering applications. This paper presents a finite element algorithm developed to perform the thermal and mechanical analysis of structural steel piping systems subjected to elevated temperatures. The new pipe element with 22 degrees of freedom has a displacement field that results from the supe...
Analysis of piping elbows in plane-bending using two different numerical models
Fonseca, E.M.M.; Melo, F.J.M.Q. de; Oliveira, C.A.M deThe piping systems are used in industrial plants subjected to any efforts. These components are constituted by straight and curved or elbow elements. Elbows attached to nozzle or straight pipes produce a stiffening effect due to the restraint of ovalization provided by the adjacent components. These elements have a small thickness and when submitted to any efforts, the excessive oval shape may reduce the struct...
Schwanoma de laringe: relato de caso
Melo,Erich Christiano M.; Tiago,Romualdo Suzano L.; Brasil,Osíris de Oliveira C.; El Hassan,Soraia; Brito,Lupércio Luz; Sá,Paula Magalhães deSchwanomas são tumores benignos, de crescimento lento, encapsulados, que surgem da bainha das células de Schwann de nervos motores, sensitivos ou cranianos, não contendo elementos nervosos. A localização na laringe é extremamente rara, existindo relatos esporádicos na literatura mundial. O objetivo deste trabalho é relatar um caso de schwanoma laríngeo atendido em nosso meio. O paciente de 82 anos de idade, sex...
Desenvolvimento de um elemento finito para análise de tensões em tubos curvos
Fonseca, E.M.M.; Melo, F.J.M.Q. de; Oliveira, C.A.M deApresenta-se uma formulação para a caracterização do estado de tensão e deformação de sistemas tubulares de parede fina usando o método dos elementos finitos. O elemento de tubo desenvolvido apresenta um campo de deslocamentos para uma casca com o modelo de deformação de semi-membrana. A solução para obter a distorção de qualquer secção do tubo necessita de condições de fronteira do tipo deslocamentos ou forças...
Influência da pressão interna na rigidez de sistemas tubulares. Desenvolvimento...
Fonseca, E.M.M.; Melo, F.J.M.Q. de; Oliveira, C.A.M deEm engenharia o uso de elementos tubulares é frequente. Estas estruturas submetidas a diversos carregamentos exigem uma análise cuidada do seu comportamento. No projecto de sistemas tubulares é importante a análise do efeito da pressão interna, por diminuir a flexibilidade dos elementos aumentando por isso a rigidez da estrutura. Apresenta-se o desenvolvimento de uma formulação para a caracterização da deformaç...
Determination of flexibility factors in curved pipes with end restraints using ...
Fonseca, E.M.M.; Melo, F.J.M.Q. de; Oliveira, C.A.M dePiping systems are structural sets used in the chemical industry, conventional or nuclear power plants and fluid transport in general-purpose process equipment. They include curved elements built as parts of toroidal thin-walled structures. The mechanical behaviour of such structural assemblies is of leading importance for satisfactory performance and safety standards of the installations. This paper presents a...
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