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Spinal brucellosis. 4 years of experience.
Lopes, C; Clínica de Doenças Infecciosas dos Hospitais, Universidade de Coimbra.; Oliveira, J; Malcata, L; Pombo, V; Da Cunha, S; Côrte-Real, RThe Authors retrospectively studied 17 patients who have been admitted to the Infectious Diseases Clinic of Coimbra University Hospital during a four year period and whose final diagnosis was brucellar spondylitis. Clinical, epidemiological, laboratory and imaging features are analyzed, as well as those related to the therapeutic schedules and outcome. Females were more often affected (70.58%) and the mean age ...
The determination of susceptibility to measles, rubella, mumps and chickenpox i...
Oliveira, J; Serviço de Doenças Infecciosas e de Patologia Clínica, Hospitais da Universidade de Coimbra.; Dias, N; Ferreira, T M; da Cunha, S; Costa, DWe present an epidemiological and serological study in 286 health care students. We found susceptibility for measles in 11.7% individuals (95% confidence interval (95% CI): 8.0-15%), for rubella: 6.7% (95% CI: 3.8-9.6%) for mumps: 12.7% (95% CI: 8.0-16.6%) and for varicella 8.5% (95% CI: 5.3-11.7%). Compared to a similar study, performed in 1992 in a population of health care workers, we found an increasing sus...
Liver involvement in HIV infection and various parasitic diseases.
Meliço-Silvestre, A; Departamento de Doenças Infecciosas, Hospitais da Universidade de Coimbra, Faculdade de Medicina de Coimbra.; Da Cunha, SDuring the course of systemic infections, the liver is an organ which is frequently involved. The pathology of the human immunodeficiency virus with all its infections, opportunistic tumours and some parasitoses, such as amebiasis, kala-azar, hydatidosis, schistosomiasis and fascioliasis, evolve into hepatic compromise. This development is what we attempt to summarise. ; During the course of systemic infection...
The prevalence of measles, rubella, mumps and chickenpox antibodies in a popula...
Oliveira, J; Serviço de Doenças Infecciosas, Hospitais da Universidade de Coimbra.; da Cunha, S; Côrte-Real, R; Sampaio, L; Dais, N; Meliço-Silvestre, AWe present an epidemiological and serological study in 409 health care workers randomly selected from the 4,103 workers of the University Hospital of Coimbra. A low level of susceptibility for measles (1.2%; 95% confidence interval (95% CI): 0.15-2.23%), rubella (2.4%; 95% CI: 0.9-3.9) and varicella (3.2%; 95% CI: 1.5-4.7%) and a very high one for mumps (17.3%; 95% CI: 13.7-21.1%), were found. Ineffectiveness o...
Comparative study of various biological markers in infection by HIV1.
Serra, J E; Infectious Diseases Clinic, Coimbra University Hospital.; Pombo, V; Côrte-Real, R; Da Cunha, S; Meliço-Silvestre, AA study was performed on 51 human immunodeficiency virus (HIV-1)-infected patients with a previous history of drug abuse. By the CDC staging system for HIV infection they were mainly in advanced stages of that infection, 67% were in IV-A and 8% in IV-CI. Patients were divided in two groups, one composed of 33 individuals who needed AZT therapy and the other of those who did not need that medication (18 patients...
Cerebral toxoplasmosis after renal transplantation. Case report and review.
Da Cunha, S; Urology and Transplant Department, Coimbra University Hospitals.; Ferreira, E; Ramos, I; Martins, R; De Freitas, L; Borges, J LInfection caused by Toxoplasma gondii is a frequent event in Portugal. When this occurs in immunocompetent individuals, it is rarely a matter of concern; the contrary occurs with immunosuppressed patients or in pregnancy. Transplant patients are treated with immunosuppressive drugs which mainly disturb their mechanisms of cellular immunity, and that opens the way to infections by opportunistic intracellular mic...
Comparative study of various biological markers in HIV 1 infection.
Serra, J E; Clínica de Doenças Infecciosas, Hospital da Universidade de Coimbra.; Pombo, V; Côrte-Real, R; da Cunha, S; Meliço-Silvestre, AA study was performed on 51 human immunodeficiency virus (HIV 1)-infected patients with a previous history of drug abuse. By the CDC staging system for HIV infection they were mainly in advanced stages of that infection, 67% were in IV-A and 8% in IV-C1. Patients were divided in two groups, one composed of 33 individuals who needed AZT therapy and the other of those who did not need that medication (18 patients...
Cerebral toxoplasmosis in a kidney transplant patient. A clinical case and revi...
da Cunha, S; Clínica de Doenças Infecciosas, Serviço de Urologia e Transplantação, Hospitais da Universidade de Coimbra.; Ferreira, E; Ramos, IInfection caused by Toxoplasma gondii is a frequent event in Portugal. When this occurs in immunocompetent individuals it is rarely a matter of concern; the contrary occurs with immunosuppressed patients or in pregnancy. Transplant patients are treated with immunosuppressive drugs which mainly disturb their mechanisms of cellular immunity, and that opens the way to infections by opportunistic intracellular micr...
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