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Sustained release of prednisone and mesalamine from diatom exoskeletons : bioin...

Zhang, H.; Shahbazi, M. A.; Mäkilä, E. M.; Silva, Tiago H.; Reis, R. L.; Salonen, J. J.; Hirvonen, J. T.; Santos, H. A.

Mesoporous silicon and silica-based particles have recently been synthesized and proposed for the controlled delivery of several drugs [1,2]. On the other hand, nature and in particular marine organisms have been the source and inspiration for the development of different biomedical applications, including drug delivery devices [3]. On the border of both rests diatoms exoskeletons, nature-made porous silica-bas...


Fetal development of regulatory mechanisms for body fluid homeostasis

Guan,J.; Mao,C.; Feng,X.; Zhang,H.; Xu,F.; Geng,C.; Zhu,L.; Wang,A.; Xu,Z.

The balance of body fluids is critical to health and the development of diseases. Although quite a few review papers have shown that several mechanisms, including hormonal and behavioral regulation, play an important role in body fluid homeostasis in adults, there is limited information on the development of regulatory mechanisms for fetal body fluid balance. Hormonal, renal, and behavioral control of body flui...

Data: 2008   |   Origem: OASIS br

Arsenic trioxide reduces the invasive and metastatic properties of nasopharynge...

Du,C.W.; Wen,B.G.; Li,D.R.; Peng,X.; Hong,C.Q.; Chen,J.Y.; Lin,Z.Z.; Hong,X.; Lin,Y.C.; Xie,L.X.; Wu,M.Y.; Zhang,H.

Nasopharyngeal carcinoma (NPC) is notorious for the metastases, which are in close association with Epstein-Barr virus-encoded latent membrane protein 1 (LMP1). Arsenic trioxide (As2O3) has been shown to induce apoptosis and differentiation in NPC xenografts. Then, can it repress the cancer cells' metastasis potential? To elucidate this issue, the present study was performed. LMP1-negative cell line HNE1 and LM...

Data: 2006   |   Origem: OASIS br

Detection of single nucleotide mutations in wheat using single strand conformat...

Martins-Lopes, Paula; Zhang, H.; Koebner, R.

Data: 2001   |   Origem: Repositório da UTAD

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Fundação para a Ciência e a Tecnologia Universidade do Minho   Governo Português Ministério da Educação e Ciência Programa Operacional da Sociedade do Conhecimento União Europeia