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Drug release from microspheres and nanospheres of poly(lactide-co-glycolide) wi...
Silva,André R. da; Zaniquelli,M. Elisabete D.; Baratti,Mariana O.; Jorge,Renato AtilioA new technique using diffuse reflectance spectroscopy was developed that enables the monitoring of encapsulated drug release without particle separation from the assayed medium. Studies of chloro(5,10,15,20-tetraphenylporphyrinato)indium(III) (InTPP) release from microspheres and nanospheres of poly(lactide-co-glycolide) (PLGA) were performed using this new technique. The release of InTPP was biphasic, with an...
Vesicle-micelle transition in aqueous mixtures of the cationic dioctadecyldimet...
Alves, Fernanda Rosa; Zaniquelli, M. Elisabete; Loh, Watson; Castanheira, Elisabete M. S.; Oliveira, M. Elisabete; Feitosa, EloiThe vesicle-micelle transition in aqueous mixtures of dioctadecyldimethylammonium and octadecyltrimethylammonium bromide (DODAB and C18TAB) cationic surfactants, having respectively double and single chain, was investigated by differential scanning calorimetry (DSC), steady state fluorescence, dynamic light scattering (DLS) and surface tension. The experiments performed at constant up to 1.0 mM total surfactant...
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