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A new 500 kb haplotype associated with high CD8+ T-lymphocyte numbers predicts ...
Cruz, E.; Whittington, C.; Krikler, S.; Mascarenhas, C.; Lacerda, R.; Vieira, J.; Porto, G.Abstract BACKGROUND: Hereditary Hemochromatosis(HH) is a common genetic disorder of iron overload where the large majority of patients are homozygous for one ancestral mutation in the HFE gene. In spite of this remarkable genetic homogeneity, the condition is clinically heterogeneous, varying from a severe disease to an asymptomatic phenotype with only abnormal biochemical parameters. The recent recognition of ...
Data: 2008
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Origem: Repositório Científico do Centro Hospitalar do Porto
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