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Interactions between cells or proteins and surfaces exhibiting extreme wettabil...
Wenlong Song; Mano, J. F."First published online 12 Feb 2013 " ; Regulation of protein adsorption and cell adhesion on surfaces is a key aspect in the field of biomedicine and tissue engineering. Beside the general studies on hydrophilic/hydrophobic surfaces, there are both fundamental and practical interests to extend the investigation of the interaction between proteins or cells and surfaces to the two extreme wettability ranges, na...
Modification of paper using polyhydroxybutyrate to obtain biomimetic superhydro...
González-Obeso, Constancio; Sousa, M. P.; Wenlong Song; Rodriguez-Perez, M. A.; Bhushan, Bharat; Mano, J. F."Available online 6 October 2012" ; Inspired in nature, the creation of synthetic superhydrophobic surfaces is nowadays a major object of study, with many potential applications in different fields. The fabrication of such substrates has been dominated by the use of non biodegradable and poorly flexible materials, using expensive and complex procedures. To overcome this issue, we propose a simple concept for f...
Superhydrophobic poly(L-lactic acid) surface as potential bacterial colonizatio...
Sousa, Cláudia; Rodrigues, Diana; Oliveira, Rosário; Wenlong Song; Mano, J. F.; Azeredo, JoanaHydrophobicity is a very important surface property and there is a growing interest in the production and characterization of superhydrophobic surfaces. Accordingly, it was recently shown how to obtain a superhydrophobic surface using a simple and cost-effective method on a polymer named poly(L-lactic acid) (PLLA). To evaluate the ability of such material as a substrate for bacterial colonization, this work ass...
Wettable arrays onto superhydrophobic surfaces for bioactivity testing of inorg...
Luz, M. Gisela; Leite, Álvaro J.; Neto, Ana I.; Wenlong Song; Mano, J. F.Poly(l-lactic acid) superhydrophobic surfaces prepared by a phase-separation methodology were treated with 30 min exposition of UV/O3 irradiation using hollowed masks in order to obtain patterned superhydrophilic squared-shaped areas. These wettable areas successfully confined bioactive glass nanoparticles (BG-NPs), by dispensing and drying individual droplets of BG-NPs suspensions. The obtained biomimetic chip...
Synthesis of temperature-responsive Dextran-MA/PNIPAAm particles for controlled...
Lima, A. C.; Wenlong Song; Blanco-Fernandez, Barbara; Alvarez-Lorenzo, Carmen; Mano, J. F.Purpose: To implement a bioinspired methodology using superhydrophobic surfaces suitable for producing smart hydro- gel beads in which the bioactive substance is introduced in the particles during their formation. Methods: Several superhydrophobic surfaces, including polystyrene, aluminum and copper, were prepared. Polymeric solutions composed by photo-crosslinked dextran-methacrylated and thermal responsive p...
High-throughput evaluation of interactions between biomaterials, proteins and c...
Neto, Ana I.; Custódio, Catarina A.; Wenlong Song; Mano, J. F.We propose a new low cost platform for high-throughput analysis that permits screening the biological performance of independent combinations of biomaterials, cells and culture media. Patterned superhydrophobic flat substrates with controlled wettable spots are used to produce microarray chips for accelerated multiplexing evaluation.
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