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Phenotypic and functional consequences of haploinsufficiency of genes from exoc...
Wen, J.; Lopes, F.; Soares, G.; Farrell, S.; Nelson, C.; Qiao, Y.; Martell, S.; Badukke, C.; Bessa, C.; Ylstra, B.; Lewis, S.; Isoherranen, N.Background Rare, recurrent genomic imbalances facilitate the association of genotype with abnormalities at the “whole body” level. However, at the cellular level, the functional consequences of recurrent genomic abnormalities and how they can be linked to the phenotype are much less investigated. Method and results We report an example of a functional analysis of two genes from a new, overlapping microdeletion...
Blast resistance of cracked steel structures repaired with CFRP composite patch
Pereira, João M.; Ghasemnejad, H.; Wen, J. X.; Lourenço, Paulo B.; Tam, V. H. Y.In this paper the blast resistance of cracked steel structures repaired with fibre-reinforced polymer (FRP) composite patch are investigated. The switch box which has been subjected to blast loading is chosen for a detailed study. For impulsively loaded structures, the structural damage and response depends on the impulse rather than the pressure pulse. In this regard, the blast wave is modelled as a uniform re...
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