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Synthesis of new beta-amidodehydroaminobutyric acid derivatives and of new tyro...

Ferreira, Paula M. T.; Pereira, Goreti; Vilaça, Helena

Several beta-amidodehydroaminobutyric acid derivatives were prepared from N,C-diprotected beta-bromodehydroaminobutyric acids and amides by a copper catalyzed C-N coupling reaction. The best reaction conditions include the use of a catalytic amount of CuI, N,N’-dimethylethylenediamine as ligand and K2CO3 as base in toluene at 110 ºC. The stereochemistry of the products was determined using NOE difference experi...





Electrochemical reduction of dehydroamino acids: Synthesis and photophysical pr...

Ferreira, Paula M. T.; Monteiro, Luís S.; Castanheira, Elisabete M. S.; Pereira, Goreti; Lopes, Carla; Vilaça, Helena

Several beta,beta-disubstituted dehydroalanines were prepared from beta,beta-dibromo or beta-bromo, beta-substituted dehydroalanines and aryl boronic acids using a Suzuki-Miyaura cross-coupling reaction. The electrochemical behaviour of these compounds was studied by cyclic voltammetry. All compounds studied showed similar reduction potentials and these were similar to the peak potential of the methyl ester of ...


High yielding synthesis of oxazole-4-carboxylates from dehydroamino acid deriva...

Pereira, Goreti; Castanheira, Elisabete M. S.; Ferreira, Paula M. T.; Monteiro, Luís S.; Vilaça, Helena






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Fundação para a Ciência e a Tecnologia Universidade do Minho   Governo Português Ministério da Educação e Ciência Programa Operacional da Sociedade do Conhecimento União Europeia