Encontrados 236 documentos, a visualizar página 1 de 24
Insights into the Synthesis of Steroidal A-Ring Olefins
Varela, Carla M.; Roleira, Fernanda M. F.; Costa, Saul C. P.; Tinto, Alexandra S. C. T.; Martins, Ana I. O. S.; Carvalho, Rui A.; Teixeira, Natércia A.one (5), from the D1-3-keto enone, (5a,17b)-3-oxo-5-androst-1-en-17-yl acetate (1), through a strategy involving the reaction of D1-3-hydroxy allylic alcohol, 3b-hydroxy-5a-androst-1-en-17b-yl acetate (2), with SOCl2 , was revisited in order to prepare and biologically evaluate 5 as aromatase inhibitor for breast cancer treatment. Surprisingly, the followed strategy also afforded the isomeric D2-olefin 6 as a b...
Physical and sport activities in school and community context : what impact on ...
Ribeiro, Jorge Manuel Pereira; Rodrigues, Luís P.; Santos, Luísa S.; Carvalho, Graça SimõesN.º especial que contém os resumos do "2nd IPLeiria International Health Congress : Challenges & Innovation in Health" ; INTRODUCTION: Health promotion interventions usually occur at school, where young people stay longer. However, physical / sport activity can be organized not only at school but also in the community. Thus, it seems important to investigate the impact of physical activities / sports, at schoo...
Evaluation of elderly persons' functionality and care needs
Lopes, M. J.; Escoval, A.; Pereira, D. G.; Pereira, C. S.; Carvalho, C.; Fonseca, C.OBJECTIVE: To evaluate the elderly persons' functionality, based on the International Classification of Functionality. METHODS: a cross-sectional, descriptive study; a stratified random sample of 903 elderly persons; a confidence level of 95%; and a margin of error of 2.5%. Questionnaire based on the International Classification of Functionality; data was collected based on structured interviews undertaken by ...
Estudo detalhado de isótopos de Nd e Sr em sedimentos do core KC 024-19 (talude...
Santos, J. F.; Martins, V.; Ribeiro, S.; Carvalho, A. T.; Matinhas, C.; Dias, J. M. A.; Rocha, F.Neste trabalho, actualizam-se os dados isotópicos de Nd e Sr que esta equipa tem vindo a obter nos últimos anos com base em amostras do core KC 024-19 (-2765 m, 42°08’98’’N, 10°29´96’’W). Este core foi colhido no talude continental da Galiza e, nele, está representada a sedimentação ocorrida nos últimos 40 ka. No nosso estudo, dá-se particular destaque aos quatro níveis de Heinrich (H1 a H4) que foram identific...
Caso dermatológico: Escabiose
Matos, C.; Machado, S.; Carvalho, S.; Dinis, M.J.; Selores, M.The authors describe a clinical case of a 5-months-old boy with widespread rash since the first month of life. Diffuse papular rash with intensive itching. The shaved skin was inconclusive so we performed biopsy to confirm the diagnosis of scabies. It’s a dermatosis very contagious caused by the mite Sarcoptes scabiei var. hominis. In infants skin eruption may have a polymorphic presentation with characteristic...
Extrusion of poly(vinylidene fluoride) recycled filaments : effect of the proce...
Silva, Marco Aurélio Pinto; Martins, R. S.; Carvalho, Helder; Nóbrega, J. M.; Lanceros-Méndez, S.This study analyses the possibility of reprocessing used poly(vinylidene fluoride), PVDF, maintaining the main properties critical for its use in piezoelectric sensor/actuator applications. The influence of multiple reprocessing cycles of PVDF on crystallinity and ß-phase content fundamental for its electroactive behaviour, was studied. Nine reprocessing cycles were completed and it was found that the material ...
Simulação numérica do comportamento de vidro reforçado com elementos metálicos ...
Valente, Isabel; Cruz, Paulo J. S.; Carvalho, Paulo L. L.; Alves, LúcioTrabalho financiado por Fundos FEDER, através do Programa Operacional Fatores de Competitividade – COMPETE, e por Fundos Nacionais, através da FCT – Fundação para a Ciência e a Tecnologia, no âmbito do projeto PTDC/ECM/116609/2010 – S-GLASS: Desempenho Estrutural e Regras de Projeto de Vigas de Vidro Reforçadas Externamente. ; O presente artigo descreve a simulação numérica de vigas de vidro laminado reforçada...
El síndrome de Mauriac todavía existe
Dias, J; Martins, S; Carvalho, S; Marques, O; Antunes, ABACKGROUND/OBJECTIVE: Mauriac syndrome (MS) is a rare complication of type 1 diabetes mellitus (DM1). It is related to low insulin concentrations and is less common since longer-acting insulins became available. It is characterized by hepatomegaly, growth and puberty delay, and the presence of elevated transaminases and serum lipids. The aim of this study was to describe the patients from a pediatric diabetic p...
Mauriac syndrome still exists
Dias, J; Martins, S; Carvalho, S; Marques, O; Antunes, ABACKGROUND/OBJECTIVE: Mauriac syndrome (MS) is a rare complication of type 1 diabetes mellitus (DM1). It is related to low insulin concentrations and is less common since longer-acting insulins became available. It is characterized by hepatomegaly, growth and puberty delay, and the presence of elevated transaminases and serum lipids. The aim of this study was to describe the patients from a pediatric diabetic p...
Peroxiredoxins are involved in two independent signalling pathways in the abiot...
Vidigal, P.; Carvalho, R.; Amâncio, S.; Carvalho, L.Peroxiredoxins (Prxs) play major roles in preventing oxidative damage and their function is consistent with the presence of Prx isoforms in most, if not all, cellular compartments and their expression is dependent on environmental conditions. The aim of this study was to identify and characterize genes encoding Prxs in Vitis vinifera. Quantitative real time polymerase chain reaction (qRT PCR) was used to determ...
| Financiadores do RCAAP | |||||||
|
|
|
|
|
|
||