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Surfaces contamination with 5-Fluorouracil in two Portuguese hospitals
Viegas, Susana; Pádua, Mário; Gomes, MárioDuring the last years there has been an increasing concern about occupational exposure to cytostatic drugs in hospitals. The first findings on occupational exposures among hospital personnel administering chemotherapy were reported only in 1979. Since then, a great number of studies have been publishing describing possible exposure-related health effects.Consequently, rigorous guidelines for the safe handling o...
Exposure to volatile organic compounds in a composting plant
Viegas, Susana; Almeida-Silva, Marina; Viegas, CarlaSome previous studies have suggested that some of the volatile organic compounds (VOCs) found in composting plants may have a toxic effect that can influence, besides surroundings populations, workers from the composting plants. Impact of waste management to the environment and workers is already recognised as an environment and occupational health concerns. Several studies regarding the VOCs and bioaerosols em...
Occupational exposure to particulate matter and fungi in a composting plant: ca...
Viegas, Susana; Almeida-Silva, Marina; Sabino, Raquel; Viegas, CarlaThe handling of waste can be responsible for occupational exposure to particles and fungi. The aim of this study was to characterize exposure to particles and fungi in a composting plant. Measurements of particulate matter were performed using portable direct-reading equipment. Air samples of 50L were collected through an impaction method with a flow rate of 140L/min onto malt extract agar supplemented with chl...
Toxicology of metals and metalloids
Barbosa Jr, Fernando; Farina, Marcelo; Viegas, Susana; Kempinas, Wilma de GravaMetal toxicology is one of the oldest areas of study of toxicology and one of the oldest environmental problems. Metals and metalloids are toxic elements at the top of the priority list of hazardous substances of the Agency for Toxic Substances and Disease Registry (ATSDR). However, several gaps of knowledge still exist that are related to their toxicity, mainly concerning the mechanisms of action. This special...
Exposure to volatile organic compounds, particulate matter and fungi in a compo...
Viegas, Susana; Almeida-Silva, Marina; Sabino, Raquel; Viegas, CarlaComposting is an important process of solid waste management and it can be used for treatment of a variety of different wastes (green waste, household waste, sewage sludge and more). This process aims to: 1. Reduce the volumes of waste and; 2. Create a valuable product which can be recycled as a soil amendment in agriculture and gardening. A natural self-heating process involving the biological degradation of o...
Surfaces contamination with 5-Fluorouracil in two Portuguese hospitals
Viegas, Susana; Gomes, Mário; Pádua, MárioBackground - The use of antineoplastic drugs in cancer therapy is increasing due to their action in cancer cells. Carcinogenic, mutagenic and teratogenic effects. Some studies demonstrated that nurses and pharmacy personnel involved in preparation or administration are exposed to antineoplastic drugs. Aim: assess 5-Fluorouracil (5-FU) contamination on the surfaces of two Portuguese Hospitals (preparation and ad...
Mammography equipment design: impact on radiographers’ practice
Costa, Stefanie; Oliveira, Eva; Reis, Cláudia; Viegas, Susana; Serranheira, FlorentinoObjectives - Identify radiographers’ postures during frequent mammography procedures related to the mammography equipment and patient characteristics. Methods - A postural task analysis was performed using images acquired during the simulation of mammography positioning procedures. Simulations included craniocaudal/(CC) and mediolateral-oblique/(MLO) positioning in three different settings: radiographers and pa...
Cytostatics occupational exposure: genotoxic effects assessment
Ladeira, Carina; Viegas, Susana; Carolino, Elisabete; Gomes, M. C.; Brito, MiguelThe use of cytostatics drugs in anticancer therapy is increasing. Health care workers can be occupationally exposed to these drugs classified as carcinogenic, mutagenic or teratogenic. Workers may be exposed to this drug, being in the hospital settings the main focus dwelled upon the pharmacy, and nursing personnel. Although the potential therapeutic benefits of hazardous drugs outweigh the risks of side effect...
Biomonitorization in hospital settings with cytostatics occupational exposure
Ladeira, Carina; Viegas, Susana; Carolino, Elisabete; Gomes, M. C.; Brito, MiguelExposure in a hospital setting is normally due to the use of several antineoplastic drugs simultaneously. Nevertheless, the effects of such mixtures at the cell level and on human health in general are unpredictable and unique due to differences in practice of hospital oncology departments, in the number of patients, protection devices available, and the experience and safety procedures of medical staff. Health...
Application of alkaline comet assay in human biomonitoring for genotoxicity: a ...
Ladeira, Carina; Viegas, Susana; Carolino, Elisabete; Gomes, M. C.; Brito, MiguelThe use of cytostatics drugs in anticancer therapy is increasing. Health care workers can be occupationally exposed to these drugs classified as carcinogenic, mutagenic or teratogenic. Cytostatics drugs are a heterogeneous group of chemicals widely used in the treatment of cancer, nevertheless have been proved to be also mutagens, carcinogens and teratogens. Workers may be exposed to this drug, being in the hos...
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